NOS1 抗体 (C-Term)
Quick Overview for NOS1 抗体 (C-Term) (ABIN350524)
抗原
See all NOS1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
原理
- Goat antibody to nNOS
-
特异性
- Specific for nNOS
-
交叉反应
- 豚鼠, 人, 小鼠, 兔, 大鼠
-
交叉反应 （详细）
- Other species not yet tested.
-
纯化方法
- IgG purified. Sterilised UV-C irradiated acidified to pH 3.5 then neutralised
-
免疫原
- Synthetic peptides from the c-terminal region of human nNOS conjugated to blue carrier protein was used as the antigen.
-
亚型
- IgG
-
-
anti-Nitric Oxide Synthase 1, Neuronal (NOS1) (C-Term) antibody
Verified NOS1 适用: 人 IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Nitric Oxide Synthase 1, Neuronal (NOS1) (AA 53-247) antibodyNOS1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase 1, Neuronal (NOS1) (AA 9-136) antibodyNOS1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase 1, Neuronal (NOS1) (AA 17-153) antibodyNOS1 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2E11G6 unconjugated
anti-Nitric Oxide Synthase 1, Neuronal (NOS1) (pSer852) antibodyNOS1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase 1, Neuronal (NOS1) (AA 1213-1337) antibodyNOS1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase 1, Neuronal (NOS1) (AA 51-150) antibodyNOS1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase 1, Neuronal (NOS1) (AA 691-826) antibodyNOS1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase 1, Neuronal (NOS1) (AA 1418-1434), (C-Term) antibodyNOS1 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase 1, Neuronal (NOS1) (AA 655-875) antibodyNOS1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- IHC WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
-
注意事项
- Avoid freeze and thaw cycles.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
-
有效期
- 12 months
-
-
- NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))
-
别名
- nNOS
-
背景
- FUNCTION: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system NO displays many properties of a neurotransmitter. Inhibitory transmitter for non-adrenergic and non-cholinergic nerves in the colorectum. CATALYTIC ACTIVITY: L-arginine + n NADPH + m O2 = citrulline + nitric oxide + n NADP+. ENZYME REGULATION: Stimulated by calcium/calmodulin. Inhibited by n-Nos-inhibiting protein (PIN) which may prevent the dimerization of the protein. Inhibited by NOSIP. SUBCELLULAR LOCATION: Cell membrane sarcolemma, Peripheral membrane protein. Cell projection dendritic spine. Note=In skeletal muscle it is localized beneath the sarcolemma of fast-twitch muscle fiber by associating with the dystrophin glycoprotein complex. In neurons enriched in dendritic spines. TISSUE SPECIFICITY: Isoform N-NOS-1 is expressed in brain and colorectum. Found in the Auerbach's plexus of the enteric nervous system. Isoform PNNOS is expressed in the penis urethra prostate and skeletal muscle and coexists with the cerebellar nnos in the pelvic plexus bladder and liver and is detectable in the cerebellum.
-
UniProt
- P29476
-
途径
- Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction
抗原
-
