M6PR 抗体
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北京 101111
Quick Overview for M6PR 抗体 (ABIN350472)
抗原
See all M6PR 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit antibody to M6PR
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特异性
- Specific for MPRD.
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交叉反应
- 人, Marmoset, 小鼠, 大鼠
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交叉反应 (详细)
- Other species not yet tested.
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纯化方法
- IgG
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免疫原
- A synthetic peptide from mouse M6PR conjugated to blue carrier protein was used as the antigen.
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亚型
- IgG
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应用备注
- IHC WB. Use at a concentration of 10-50 μg,ml. The optimal dilution should be determined by the end user. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
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注意事项
- Avoid freeze and thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
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有效期
- 12 months
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- M6PR (Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR))
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别名
- M6PR
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背景
- FUNCTION: Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. SUBUNIT: Homodimer. Binds GGA1 GGA2 and GGA3. SUBCELLULAR LOCATION: Lysosome membrane, Single-pass type I membrane protein.
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UniProt
- P24668
抗原
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