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Huntingtin 抗体 (AA 1150-1200)

This anti-Huntingtin antibody is a 兔 多克隆 antibody detecting Huntingtin in IHC 和 WB. Suitable for 大鼠.
产品编号 ABIN350377
发货至: 中国

Quick Overview for Huntingtin 抗体 (AA 1150-1200) (ABIN350377)

抗原

See all Huntingtin (HTT) 抗体
Huntingtin (HTT)

适用

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大鼠

宿主

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克隆类型

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多克隆

标记

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This Huntingtin antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Western Blotting (WB)
  • 抗原表位

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    AA 1150-1200

    原理

    Rabbit antibody to Huntingtin

    特异性

    Specific for Huntingtin.

    交叉反应

    小鼠, 大鼠

    交叉反应 (详细)

    Other species not yet tested.

    纯化方法

    IgG

    免疫原

    A synthetic peptide from AA 1150-1200 of rat Huntingtin conjugated to blue carrier protein was used as the antigen. The peptide shares 87% identity with mouse and human sequences.

    亚型

    IgG
  • 应用备注

    IHC WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.

    注意事项

    Avoid freeze and thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

    有效期

    12 months
  • 抗原

    Huntingtin (HTT)

    别名

    Huntingtin

    背景

    FUNCTION: May play a role in microtubule-mediated transport or vesicle function. SUBCELLULAR LOCATION: Cytoplasm. Nucleus. TISSUE SPECIFICITY: Expressed to a high degree in all the regions of the brain of adults and in meiotic cells of the testis. In addition very low levels are detected in various non-neuronal tissues (heart muscle liver lung and kidney). DEVELOPMENTAL STAGE: Identified at high levels in neuronal tissues of embryos as early as day 14.5. This expression remains constant in all further development stages (up to the adult). On the other hand the expression in non-neuronal tissues is down-regulated from stage 17.5 day old embryos.

    UniProt

    P51111

    途径

    PI3K-Akt Signaling, Hormone Transport, Transition Metal Ion Homeostasis, Tube Formation, Protein targeting to Nucleus, Dicarboxylic Acid Transport
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