Huntingtin 抗体 (AA 1150-1200)
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- 抗原 See all Huntingtin (HTT) 抗体
- Huntingtin (HTT)
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抗原表位
- AA 1150-1200
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Huntingtin antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Western Blotting (WB)
- 特异性
- Specific for Huntingtin.
- 交叉反应
- 小鼠, 大鼠
- 交叉反应 (详细)
- Other species not yet tested.
- 纯化方法
- IgG
- 免疫原
- A synthetic peptide from AA 1150-1200 of rat Huntingtin conjugated to blue carrier protein was used as the antigen. The peptide shares 87% identity with mouse and human sequences.
- 亚型
- IgG
- Top Product
- Discover our top product HTT Primary Antibody
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- 应用备注
- IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
- 注意事项
- Avoid freeze and thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
- 有效期
- 12 months
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- 抗原
- Huntingtin (HTT)
- 别名
- Huntingtin (HTT 产品)
- 背景
- FUNCTION: May play a role in microtubule-mediated transport or vesicle function. SUBCELLULAR LOCATION: Cytoplasm. Nucleus. TISSUE SPECIFICITY: Expressed to a high degree in all the regions of the brain of adults and in meiotic cells of the testis. In addition, very low levels are detected in various non-neuronal tissues (heart, muscle, liver, lung and kidney). DEVELOPMENTAL STAGE: Identified at high levels in neuronal tissues of embryos as early as day 14.5. This expression remains constant in all further development stages (up to the adult). On the other hand the expression in non-neuronal tissues is down-regulated from stage 17.5 day old embryos.,Neurodegeneration,Huntington disease protein homolog, Htt, HD protein homolog
- UniProt
- P51111
- 途径
- PI3K-Akt Signaling, Hormone Transport, Transition Metal Ion Homeostasis, Tube Formation, Protein targeting to Nucleus, Dicarboxylic Acid Transport
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