HCN1 抗体 (AA 400-450)
Quick Overview for HCN1 抗体 (AA 400-450) (ABIN350360)
抗原
See all HCN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 400-450
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原理
- Sheep antibody to HCN1
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特异性
- Specific for HCN1.
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交叉反应
- 人, 小鼠, 大鼠
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交叉反应 （详细）
- Other species not yet tested.
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纯化方法
- IgG
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免疫原
- A synthetic peptide from AA 400-450 of human HCN1 conjugated to an immunogenic carrier protein was used as the antigen.
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亚型
- IgG
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anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) (AA 778-910) antibody
HCN1 适用: 大鼠 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal S70 unconjugated
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) (AA 778-910) antibody (HRP)HCN1 适用: 大鼠 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal S70 HRP
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) (AA 778-910) antibody (FITC)HCN1 适用: 大鼠 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal S70 FITC
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) (AA 778-910) antibody (Biotin)HCN1 适用: 大鼠 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal S70 Biotin
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) (AA 778-910) antibody (PE)HCN1 适用: 大鼠 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal S70 PE
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) (AA 778-910) antibody (PerCP)HCN1 适用: 大鼠 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal S70 PerCP
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) (AA 778-910) antibody (APC)HCN1 适用: 大鼠 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal S70 APC
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) (AA 778-910) antibody (Atto 488)HCN1 适用: 大鼠 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal S70 Atto 488
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) (AA 778-910) antibody (Atto 594)HCN1 适用: 大鼠 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal S70 Atto 594
anti-Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1) (AA 778-910) antibody (Atto 390)HCN1 适用: 大鼠 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal S70 Atto 390
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应用备注
- IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
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注意事项
- Avoid freeze and thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
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有效期
- 12 months
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- HCN1 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1))
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别名
- HCN1
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背景
- FUNCTION: Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). Activated by cAMP and at 10-100 times higher concentrations also by cGMP. May mediate responses to sour stimuli. SUBUNIT: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming subunits. Heteromultimer with HCN2. Interacts with KCNE2. SUBCELLULAR LOCATION: Membrane, Multi-pass membrane protein. TISSUE SPECIFICITY: Detected in brain in particular in amygdala and hippocampus while expression in caudate nucleus corpus callosum substantia nigra subthalamic nucleus and thalamus is very low or not detectable. Detected at very low levels in muscle and pancreas. DOMAIN: The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
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UniProt
- O60741
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途径
- Asymmetric Protein Localization
抗原
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