DRAM 抗体 (AA 160-210)
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Quick Overview for DRAM 抗体 (AA 160-210) (ABIN350295)
抗原
See all DRAM (DRAM1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 160-210
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原理
- Rabbit antibody to DRAM
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特异性
- Specific for DRAM.
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交叉反应
- 人, 小鼠, 大鼠
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交叉反应 （详细）
- Other species not yet tested.
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纯化方法
- IgG
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免疫原
- A synthetic peptide from AA 160-210 of human DRAM conjugated to blue carrier protein has been used as the antigen. The antigen shares 85% identity with mouse's and rat's.
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亚型
- IgG
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anti-DNA-Damage Regulated Autophagy Modulator 1 (DRAM1) (AA 50-100) antibody
DRAM1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-DNA-Damage Regulated Autophagy Modulator 1 (DRAM1) (AA 70-119) antibodyDRAM1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-DNA-Damage Regulated Autophagy Modulator 1 (DRAM1) (N-Term) antibodyDRAM1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-DNA-Damage Regulated Autophagy Modulator 1 (DRAM1) (C-Term) antibodyDRAM1 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-DNA-Damage Regulated Autophagy Modulator 1 (DRAM1) (N-Term) antibodyDRAM1 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA, IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC WB. Use at a concentration of 10-50 μg,ml. The optimal working concentration should be determined by the end user. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
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注意事项
- Avoid freeze and thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
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有效期
- 12 months
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- DRAM (DRAM1) (DNA-Damage Regulated Autophagy Modulator 1 (DRAM1))
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别名
- DRAM
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背景
- This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4. FUNCTION: Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73-mediated autophagy. SUBCELLULAR LOCATION: Lysosome membrane, Multi-pass membrane protein. INDUCTION: By p53/TP53 and p73/TP73. Directly activated by p53/TP53. Significantly down-regulated in tumor cell lines by methylation-dependent transcriptional silencing.
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UniProt
- Q8N682
抗原
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