COPD (AA 150-200) 抗体
This anti- antibody is a 兔 多克隆 antibody detecting in WB 和 IHC. Suitable for 人.
Quick Overview for COPD (AA 150-200) 抗体 (ABIN350257)
抗原
COPD
适用
人
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
Western Blotting (WB), Immunohistochemistry (IHC)
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抗原表位
- AA 150-200
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原理
- Rabbit antibody to COPD (150-200)
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特异性
- Specific for COPD.
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交叉反应
- 人, 小鼠, 大鼠
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交叉反应 （详细）
- Other species not yet tested.
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纯化方法
- IgG
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免疫原
- A synthetic peptide from AA 150-200 of human COPD conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat mouse and xenopus.
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亚型
- IgG
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应用备注
- IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
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注意事项
- Avoid freeze and thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
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有效期
- 12 months
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- COPD
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背景
- FUNCTION: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles which further mediate biosynthetic protein transport from the ER via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs) which are small GTP-binding proteins, the complex also influences the Golgi structural integrity as well as the processing activity and endocytic recycling of LDL receptors. SUBCELLULAR LOCATION: Cytoplasm. Golgi apparatus membrane, Peripheral membrane protein, Cytoplasmic side. Cytoplasmic vesicle COPI-coated vesicle membrane, Peripheral membrane protein, Cytoplasmic side. Note: The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi as well as on the vesicles/buds originating from it.
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UniProt
- P48444
抗原
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