电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Cofilin 抗体

This anti-Cofilin antibody is a 绵羊 多克隆 antibody detecting Cofilin in WB 和 IHC. Suitable for 人.
产品编号 ABIN350240
发货至: 中国

Quick Overview for Cofilin 抗体 (ABIN350240)

抗原

See all Cofilin (CFL1) 抗体
Cofilin (CFL1) (Cofilin 1 (CFL1))

适用

  • 148
  • 95
  • 92
  • 7
  • 5
  • 5
  • 4
  • 1
  • 1
  • 1
  • 1

宿主

  • 142
  • 24
  • 1
  • 1
绵羊

克隆类型

  • 141
  • 26
多克隆

标记

  • 87
  • 11
  • 10
  • 7
  • 7
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Cofilin antibody is un-conjugated

应用范围

  • 90
  • 63
  • 61
  • 47
  • 41
  • 41
  • 37
  • 36
  • 24
  • 22
  • 13
  • 7
  • 3
  • 3
  • 3
  • 2
  • 2
Western Blotting (WB), Immunohistochemistry (IHC)
  • 原理

    Sheep antibody to Cofilin-1

    特异性

    Specific for Cofilin-1.

    交叉反应

    人, 小鼠, 大鼠

    交叉反应 (详细)

    Other species not yet tested.

    纯化方法

    IgG

    免疫原

    A synthetic peptide from the phospho Y140 & S156 of human Cofilin-1 (Cofilin non-muscle isoform) conjugated to blue carrier protein was used as the antigen. The antigen is homologous in rat mouse and monkey.

    亚型

    IgG
  • 应用备注

    IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. This antibody may also recognice the unphosphorylated form. Not tested in other applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

    注意事项

    Avoid freeze and thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

    有效期

    12 months
  • 抗原

    Cofilin (CFL1) (Cofilin 1 (CFL1))

    别名

    Cofilin-1

    背景

    FUNCTION: Controls reversibly actin polymerization and depolymerization in a pH -sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods. SUBCELLULAR LOCATION: Nucleus matrix. Cytoplasm cytoskeleton. Note: Almost completely in nucleus in cells exposed to heat shock or 10 % dimethyl sulfoxide. TISSUE SPECIFICITY: Widely distributed in various tissues.

    UniProt

    P23528

    途径

    Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events
You are here:
Chat with us!