CHMP6 抗体 (C-Term)
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- 抗原 See all CHMP6 抗体
- CHMP6 (Charged Multivesicular Body Protein 6 (CHMP6))
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抗原表位
- C-Term
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CHMP6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- Specific for CHMP6.
- 交叉反应
- 小鼠, 大鼠
- 交叉反应 （详细）
- Other species not yet tested.
- 纯化方法
- IgG
- 免疫原
- A synthetic peptide from the c-terminal region of mouse CHMP6 conjugated to an immunogenic carrier protein was used as the antigen. The antigen shares 95% identity with rat's.
- 亚型
- IgG
- Top Product
- Discover our top product CHMP6 Primary Antibody
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anti-Charged Multivesicular Body Protein 6 (CHMP6) (AA 2-201) antibody
CHMP6 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 6 (CHMP6) antibodyCHMP6 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 6 (CHMP6) antibodyCHMP6 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IHC, WB. Use at a concentration of 10-50 μg,ml. The optimal dilution should be determined by the end user. Not yet tested in other applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
- 注意事项
- Avoid freeze and thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
- 有效期
- 12 months
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- 抗原
- CHMP6 (Charged Multivesicular Body Protein 6 (CHMP6))
- 别名
- CHMP6 (CHMP6 产品)
- 背景
- FUNCTION: Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-III complex is probably involved in the concentration of MVB cargo. In the ESCRT-III complex, it probably serves as an acceptor for ESCRT-II complex on endosomal membranes. SUBUNIT: Component of the endosomal sorting required for transport complex III (ESCRT-III), at least composed of CHMP1A, CHMP1B, CHMP2A, CHMP2B, CHMP3/VPS24, CHMP4A/SHAX2, CHMP4B/SHAX1, CHMP4C/SHAX3, CHMP5/SNF7DC2 and CHMP6/VPS20. In the complex, it interacts directly with CHMP4A, CHMP4B and CHMP4C. Interacts directly with SNF8, VPS25 and VPS36 components of the ESCRT-II complex. SUBCELLULAR LOCATION: Intracytoplasmic membrane. Endosome membrane, Lipid-anchor . Note: Localizes to endosomal membranes.,Vesicle Protein Sorting,Charged multivesicular body protein 6, Chromatin-modifying protein 6
- UniProt
- P0C0A3
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