CHMP3 抗体 (N-Term)
Quick Overview for CHMP3 抗体 (N-Term) (ABIN350226)
抗原
See all CHMP3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Rabbit antibody to VPS24
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特异性
- Specific for CHMP3.
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交叉反应
- 人, 小鼠, 大鼠
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交叉反应 （详细）
- Other species not yet tested.
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纯化方法
- IgG
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免疫原
- A synthetic peptide from the n-terminal of human VPS24 conjugated to an immunogenic carrier protein was used as the antigen. The antigen is homologous in rat and mouse.
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亚型
- IgG
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anti-Charged Multivesicular Body Protein 3 (CHMP3) (AA 28-61), (N-Term) antibody
CHMP3 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB51722 unconjugated
anti-Charged Multivesicular Body Protein 3 (CHMP3) (AA 28-77) antibodyCHMP3 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 3 (CHMP3) antibodyCHMP3 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
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应用备注
- IHC WB. Use at a concentration of 10-50,micro,g,ml. The optimal dilution should be determined by the end user. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
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注意事项
- Avoid freeze and thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
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有效期
- 12 months
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- CHMP3 (Charged Multivesicular Body Protein 3 (CHMP3))
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别名
- VPS24
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背景
- FUNCTION: Component of the ESCRT-III complex which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-III complex is probably involved in the concentration of MVB cargo. Required for sorting/trafficking of EGF receptor. In case of infection the HIV-1 virus takes advantage of the ESCRT-III complex for budding and exocytic cargos of viral proteins. SUBCELLULAR LOCATION: Cytoplasm cytosol. Membrane, Lipid-anchor. TISSUE SPECIFICITY: Widely expressed. Expressed in heart brain placenta lung liver skeletal muscle kidney and pancreas.
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UniProt
- Q9Y3E7
抗原
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