Ubiquitin 抗体 (N-Term)
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Quick Overview for Ubiquitin 抗体 (N-Term) (ABIN350073)
抗原
See all Ubiquitin (Ub) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Goat antibody to Ubiquitin
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特异性
- Specific for AUP1.
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交叉反应
- 人, 小鼠, 兔, 大鼠
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交叉反应 (详细)
- Other species not yet tested.
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纯化方法
- IgG
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免疫原
- A synthetic pentamer-peptide from the n-terminal region of human ancient ubiquitous protein 1 (AUP1) conjugated to blue carrier protein was used as the antigen.
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亚型
- IgG
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应用备注
- IHC WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. This antibody works nicely in both paraffin,frozen sections. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
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注意事项
- Avoid freeze and thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
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有效期
- 12 months
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- Ubiquitin (Ub)
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别名
- Ubiquitin
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背景
- This gene encodes a protein that contains a domain with homology to the ancient conserved region of the archain 1 gene and a domain that may be involved in binding ubiquitin-conjugating enzymes. The protein encoded by this gene has been shown to bind to the conserved membrane-proximal sequence of the cytoplasmic tail of integrin alpha(IIb) subunits. These subunits play a crucial role in the integrin alpha(IIb)beta(3) inside-out signalling in platelets and megakaryocytes that leads to platelet aggregation and thrombus formation. This gene overlaps the gene for mitochondrial serine protease 25.
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UniProt
- A1L134
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途径
- Mitotic G1-G1/S Phases, Ubiquitin Proteasome Pathway
抗原
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