ACCN1 抗体 (AA 470-503)
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北京 101111
Quick Overview for ACCN1 抗体 (AA 470-503) (ABIN7698799)
抗原
See all ACCN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 470-503
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原理
- Rabbit antibody to ASIC2 (470-503)
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特异性
- Specific for ASIC2.
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交叉反应
- 人, 小鼠, 大鼠
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交叉反应 (详细)
- Other species not yet tested.
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纯化方法
- IgG
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免疫原
- A synthetic peptide from AA 470-503 of human ASIC2 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse.
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亚型
- IgG
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应用备注
- IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
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注意事项
- Avoid freeze and thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
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有效期
- 12 months
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- ACCN1 (Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1))
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别名
- ASIC2
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背景
- FUNCTION: Cation channel with high affinity for sodium which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems to modulate. SUBUNIT: Homotetramer or heterotetramer with other ASIC proteins. Interacts with STOM. Interacts with PRKCABP and ACCN3. SUBCELLULAR LOCATION: Cell membrane, Multi-pass membrane protein. Note: Localized at the plasma membrane of neurons in the soma and punctated peripheral processes.
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UniProt
- Q16515
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途径
- Sensory Perception of Sound
抗原
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