POGZ 抗体 (N-Term)
Quick Overview for POGZ 抗体 (N-Term) (ABIN349593)
抗原
See all POGZ 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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Supplier Product No.
- 600-401-a89
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Supplier
- Rockland
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原理
- Pogz Antibody
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交叉反应 （详细）
- This antibody is known to react with mouse Pogz protein.
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产品特性
- Synonyms: rabbit anti-POGZ antibody, pogo transposable element with ZNF domain antibody, Suppressor of hairy wing homolog 5, Zinc finger protein 280E, Zinc finger protein 635, SUHW5, ZNF280E, ZNF635
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纯化方法
- This product was affinity purified from monospecific antiserum by immunoaffinity chromatography.
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过滤
- Sterile filtered
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免疫原
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Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region near the N-terminus of mouse Pogz protein.
Immunogen Type: Conjugated Peptide
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亚型
- IgG
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anti-Pogo Transposable Element with ZNF Domain (POGZ) (AA 1-1357) antibody
POGZ 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Pogo Transposable Element with ZNF Domain (POGZ) (N-Term) antibodyPOGZ 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 马, Bat, 猴, Hamster, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Pogo Transposable Element with ZNF Domain (POGZ) (N-Term) antibodyPOGZ 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pogo Transposable Element with ZNF Domain (POGZ) (AA 1-300) antibodyPOGZ 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pogo Transposable Element with ZNF Domain (POGZ) (N-Term) antibodyPOGZ 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pogo Transposable Element with ZNF Domain (POGZ) (C-Term) antibodyPOGZ 适用: 人, 小鼠, 大鼠, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Pogo Transposable Element with ZNF Domain (POGZ) (AA 121-170) antibodyPOGZ 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Bat, 猴, Hamster, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Pogo Transposable Element with ZNF Domain (POGZ) (Middle Region) antibodyPOGZ 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Pogo Transposable Element with ZNF Domain (POGZ) (C-Term) antibodyPOGZ 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Application Note: This affinity purified antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 155 kDa in size corresponding to Pogz by western blotting in the appropriate cell lysate or extract.
Western Blot Dilution: 1:2,000 to 1:20,000
ELISA Dilution: 1:100,000 - 1:400,000
Other: User Optimized
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.6 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- POGZ (Pogo Transposable Element with ZNF Domain (POGZ))
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别名
- Pogz
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背景
- Background: This antibody is designed, produced, and validated as part of a collaboration with the National Cancer Institute (NCI) and is suitable for Cancer, Immunology and Nuclear Signaling research. Pogz is a zinc-finger protein containing at least 8 C2H2 zinc fingers, a CENP-B (centromere protein-B) domain, and a DDE domain found in the bacterial transposase/retroviral integrase family. Members of this family of integrases share structural homologies and show similar catalytic activity to the RAG1 and RAG2 proteins that initiate V(D)J recombination in lymphoid progenitors. Mouse Pogz has a human homolog with a base pair similarity of 90 % and amino acid similarity of 93 % for the full length protein. In humans at least 3 variants have been predicted and they are all similar at the N-terminus. A number of expressed sequence tags (ESTs) cloned from murine undifferentiated ES cells and Lin-/c-Kit+/Sca-1+ hematopoietic stem cell cDNA libraries correspond to the Pogz gene, further underlining an important function for this gene in stem cells. In mice, deletion of the gene in all tissues early in embryogenesis has been shown to be lethal.
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基因ID
- 229584
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UniProt
- Q8BZH4
抗原
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