PTENP1 抗体 (N-Term)
Quick Overview for PTENP1 抗体 (N-Term) (ABIN349585)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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Supplier Product No.
- 600-401-a90
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Supplier
- Rockland
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原理
- PTEN-P1 Antibody
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交叉反应 （详细）
- This affinity-purified antibody is directed against human PTEN protein.
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产品特性
- Synonyms: rabbit anti-PTEN-P1 antibody, Phosphatase and tensin homolog 2, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, Mutated in multiple advanced cancers 1, Phosphatase and tensin homolog, PTEN, MMAC1, TEP1
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纯化方法
- The product was affinity purified from monospecific antiserum by immunoaffinity purification.
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过滤
- Sterile filtered
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免疫原
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Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to amino acids near the N-terminal end of human PTEN-P1 protein.
Immunogen Type: Conjugated Peptide
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亚型
- IgG
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anti-Phosphatase and Tensin Homolog Pseudogene 1 (PTENP1) (AA 1-369) antibody
PTENP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Phosphatase and Tensin Homolog Pseudogene 1 (PTENP1) (N-Term) antibodyPTENP1 适用: 人, Chimpanzee, 犬, Macaque, 小鼠, 大鼠, Green Pufferfish, 斑马鱼 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Application Note: This affinity purified antibody has been tested for use in ELISA and western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 55 kDa in size corresponding to PTEN-P1 protein by western blotting in the appropriate cell lysate or extract.
Western Blot Dilution: 1:500 to 1:2,000
ELISA Dilution: 1:160,000
Other: User Optimized
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.15 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- PTENP1 (Phosphatase and Tensin Homolog Pseudogene 1 (PTENP1))
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别名
- PTEN-P1
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背景
- Background: This gene (PTENP1) is a highly homologous pseudogene of PTEN. PTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. PTEN is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tension like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway.
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基因ID
- 5728, 73765544
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UniProt
- O43460
抗原
-
