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Prosaposin 抗体

The 兔 多克隆 anti-Prosaposin antibody is suitable to detect Prosaposin in samples from 人. It has been validated for WB, ELISA 和 ICC.
产品编号 ABIN347759
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Prosaposin 抗体 (ABIN347759)

抗原

See all Prosaposin (PSAP) 抗体
Prosaposin (PSAP)

适用

  • 58
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宿主

  • 58
  • 16

克隆类型

  • 49
  • 25
多克隆

标记

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This Prosaposin antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
  • 特异性

    Reacts with human Saposin-B

    交叉反应 (详细)

    May cross react with proteins from other species due to sequence homology

    纯化方法

    Antiserum

    免疫原

    Synthetic peptide derived from an internal domain of human PSAP

    亚型

    IgG
  • 应用备注

    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only :
    ICC1:200 - 1:1 000 WB1:500 - 1:5 000

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Must be reconstituted in distilled water.

    储存条件

    4 °C/-20 °C

    储存方法

    Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

    有效期

    24 months
  • 抗原

    Prosaposin (PSAP)

    别名

    Proactivator Polypeptide Domain Saposin-B (PSAP)

    背景

    The lysosomal degradation of sphingolipids takes place by the sequential action of specific hydrolases. Some of these enzymes require specific low-molecular mass, non-enzymic proteins: the sphingolipids activator proteins (coproteins). Saposin-A and saposin-C stimulate the hydrolysis of glucosylceramide by beta-glucosylceramidase and galactosylceramide by beta-galactosylceramidase. Saposin-C apparently acts by combining with the enzyme and acidic lipid to form an activated complex, rather than by solubilizing the substrate. Saposin-B stimulates the hydrolysis of galacto-cerebroside sulfate by arylsulfatase A, GM1 gangliosides by beta-galactosidase and globotriaosylceramide by alpha-galactosidase A. Saposin-B forms a solubilizing complex with the substrates of the sphingolipid hydrolases. Saposin-D is a specific sphingomyelin phosphodiesterase activator.

    基因ID

    5660

    UniProt

    P07602

    途径

    Positive Regulation of Endopeptidase Activity
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