TTC3 抗体 (N-Term)
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Quick Overview for TTC3 抗体 (N-Term) (ABIN347721)
抗原
See all TTC3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- Reacts with human E3 ubiquitin-protein ligase TTC3
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纯化方法
- Antiserum
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免疫原
- Synthetic peptide derived from Cter domain of human TTC3
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亚型
- IgG
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anti-Tetratricopeptide Repeat Domain 3 (TTC3) (AA 1-110) antibody
TTC3 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Tetratricopeptide Repeat Domain 3 (TTC3) (AA 1-110) antibodyTTC3 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2D10 unconjugated
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应用备注
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
IF(1:100 - 1:500) WB(1:500 - 1:5000) -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Must be reconstituted in distilled water.
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储存条件
- 4 °C/-20 °C
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储存方法
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
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有效期
- 24 months
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- TTC3 (Tetratricopeptide Repeat Domain 3 (TTC3))
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别名
- E3 ubiquitin-protein ligase TTC3
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背景
- E3 ubiquitin-protein ligase that mediates the ubiquitination and subsequent degradation of phosphorylated Akt (AKT1, AKT2 and AKT3) in the nucleus. Acts as a terminal regulator of Akt signaling after activation, its phosphorylation by Akt, which is a prerequisite for ubiquitin ligase activity, suggests the existence of a regulation mechanism required to control Akt levels after activation. Catalyzes the formation of 'Lys-48'-polyubiquitin chains. May play a role in neuronal differentiation inhibition via its interaction with CIT.
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UniProt
- P53804
抗原
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