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PLCz1 抗体 (Internal Region)

This 兔 多克隆 antibody specifically detects PLCz1 in ELISA, WB, IHC 和 ICC. It exhibits reactivity toward 人. It has been mentioned in 2+ publications
产品编号 ABIN347397
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PLCz1 抗体 (Internal Region) (ABIN347397)

抗原

See all PLCz1 抗体
PLCz1 (Phospholipase C zeta 1 (PLCz1))

适用

  • 21
  • 15
  • 4

宿主

  • 36
  • 1

克隆类型

  • 36
  • 1
多克隆

标记

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  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
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This PLCz1 antibody is un-conjugated

应用范围

  • 13
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  • 3
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ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
  • 抗原表位

    • 15
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region

    特异性

    Reacts with human PLC zeta protein

    交叉反应 (详细)

    No cross reaction

    纯化方法

    Antiserum

    免疫原

    Synthetic peptide derived from internal part of PLC-zeta-1

    亚型

    IgG
  • 应用备注

    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only:
    WB(1:100 - 1:1000) ICC(1:50 - 1:1000)

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Must be reconstituted in distilled water.

    储存条件

    4 °C/-20 °C

    储存方法

    Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

    有效期

    24 months
  • Janghorban-Laricheh, Ghazavi-Khorasgani, Tavalaee, Zohrabi, Abbasi, Nasr-Esfahani: "An association between sperm PLCζ levels and varicocele?" in: Journal of assisted reproduction and genetics, (2016) (PubMed).

    Kamali-Dolat Abadi, Tavalaee, Shahverdi, Nasr-Esfahani: "Evaluation of PLCζ and PAWP Expression in Globozoospermic Individuals." in: Cell journal, Vol. 18, Issue 3, pp. 438-45, (2016) (PubMed).

  • 抗原

    PLCz1 (Phospholipase C zeta 1 (PLCz1))

    别名

    Phospholipase C zeta Isoform (PLC-zeta-1)

    背景

    The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca2+-dependent manner. Triggers intracellular Ca2+ oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion.

    基因ID

    89869

    UniProt

    Q86YW0
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