PLCz1 抗体 (Internal Region)
Quick Overview for PLCz1 抗体 (Internal Region) (ABIN347397)
抗原
See all PLCz1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- Reacts with human PLC zeta protein
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交叉反应 (详细)
- No cross reaction
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纯化方法
- Antiserum
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免疫原
- Synthetic peptide derived from internal part of PLC-zeta-1
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亚型
- IgG
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应用备注
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
WB(1:100 - 1:1000) ICC(1:50 - 1:1000) -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Must be reconstituted in distilled water.
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储存条件
- 4 °C/-20 °C
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储存方法
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
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有效期
- 24 months
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- PLCz1 (Phospholipase C zeta 1 (PLCz1))
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别名
- Phospholipase C zeta Isoform (PLC-zeta-1)
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背景
- The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca2+-dependent manner. Triggers intracellular Ca2+ oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion.
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基因ID
- 89869
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UniProt
- Q86YW0
抗原
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