Caldesmon 抗体
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北京 101111
Quick Overview for Caldesmon 抗体 (ABIN347045)
抗原
See all Caldesmon (CALD1) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Reacts with human L-Caldesmon
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纯化方法
- Antiserum
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免疫原
- A 15 residue synthetic peptide derived from human L-Caldesmon
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亚型
- IgG
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应用备注
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC(1:50 - 1:500) WB(1:200- 1:5000) -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Must be reconstituted in distilled water.
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储存条件
- 4 °C/-20 °C
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储存方法
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
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有效期
- 24 months
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- Caldesmon (CALD1) (Caldesmon 1 (CALD1))
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别名
- L-Caldesmon
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背景
- Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also play an essential role during cellular mitosis and receptor capping. Involved in Schwann cell migration during peripheral nerve regeneration
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基因ID
- 800
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UniProt
- Q05682
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途径
- Myometrial Relaxation and Contraction
抗原
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