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DPYSL3 抗体 (C-Term)

Cited in 5+ publications. This 兔 多克隆 anti-DPYSL3 antibody specifically detects DPYSL3 in WB, ELISA 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN347041
发货至: 中国
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Quick Overview for DPYSL3 抗体 (C-Term) (ABIN347041)

抗原

See all DPYSL3 抗体
DPYSL3 (Dihydropyrimidinase-Like 3 (DPYSL3))

适用

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宿主

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克隆类型

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多克隆

标记

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This DPYSL3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    特异性

    Reacts with 65 kDa CRMP-4 from human rat and mouse

    交叉反应 (详细)

    Do not react with CRMP-1, CRMP-2, CRMP-3 or CRMP-5.

    纯化方法

    Antiserum

    免疫原

    A 15 residue synthetic peptide derived from C-terminal domain of human collapsing-response mediator

    亚型

    IgG
  • 应用备注

    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only :
    -IHC : 1/500 - WB :1/2 000

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Must be reconstituted in distilled water.

    储存条件

    4 °C/-20 °C

    储存方法

    Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

    有效期

    24 months
  • Blasco, Bernard-Marissal, Vourch, Guettard, Sunyach, Augereau, Khederchah, Mouzat, Antar, Gordon, Veyrat-Durebex, Besson, Andersen, Salachas, Meininger, Camu, Pettmann, Andres, Corcia: "A rare motor neuron deleterious missense mutation in the DPYSL3 (CRMP4) gene is associated with ALS." in: Human mutation, Vol. 34, Issue 7, pp. 953-60, (2013) (PubMed).

    Bretin, Reibel, Charrier, Maus-Moatti, Auvergnon, Thevenoux, Glowinski, Rogemond, Prémont, Honnorat, Gauchy: "Differential expression of CRMP1, CRMP2A, CRMP2B, and CRMP5 in axons or dendrites of distinct neurons in the mouse brain." in: The Journal of comparative neurology, Vol. 486, Issue 1, pp. 1-17, (2005) (PubMed).

    Ricard, Rogemond, Charrier, Aguera, Bagnard, Belin, Thomasset, Honnorat: "Isolation and expression pattern of human Unc-33-like phosphoprotein 6/collapsin response mediator protein 5 (Ulip6/CRMP5): coexistence with Ulip2/CRMP2 in Sema3a- sensitive oligodendrocytes." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 21, Issue 18, pp. 7203-14, (2001) (PubMed).

    Honnorat, Byk, Kusters, Aguera, Ricard, Rogemond, Quach, Aunis, Sobel, Mattei, Kolattukudy, Belin, Antoine: "Ulip/CRMP proteins are recognized by autoantibodies in paraneoplastic neurological syndromes." in: The European journal of neuroscience, Vol. 11, Issue 12, pp. 4226-32, (2000) (PubMed).

    Balin, Loewy, Appelt: "Analysis of transglutaminase-catalyzed isopeptide bonds in paired helical filaments and neurofibrillary tangles from Alzheimer's disease." in: Methods in enzymology, Vol. 309, pp. 172-86, (1999) (PubMed).

  • 抗原

    DPYSL3 (Dihydropyrimidinase-Like 3 (DPYSL3))

    别名

    Collapsin Response Mediator Protein 4 (CRMP-4)

    背景

    Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration

    UniProt

    Q14195
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