Ochratoxin A 抗体
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北京 101111
Quick Overview for Ochratoxin A 抗体 (ABIN343805)
抗原
适用
宿主
克隆类型
标记
应用范围
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特异性
- Reacts with ochratoxin A from Aspergillus ochraceus. Crossreaction with ochratoxin B - 2%
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纯化方法
- polyclonal affinity purified on Protein A IgGs
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免疫原
- ochratoxin A conjugated to BSA
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亚型
- IgG
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- purified IgGs were dialysed against bidest. water and lyophilised
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储存条件
- 4 °C
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- Ochratoxin A
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背景
- Ochratoxin A, a toxin produced by Aspergillus ochraceus and Penicillium verrucosum, is one of the most abundant food-contaminating mycotoxins in the world. Human exposure occurs mainly through consumption of improperly stored food products, particularly contaminated grain and pork products, as well as coffee, wine grapes and dried grapes. The toxin has been found in the tissues and organs of animals, including human blood and breast milk. Ochratoxin A can cause immunosuppression and immunotoxicity in animals. The toxin's immunosuppressant activity in animals may include depressed antibody responses, reduced size of immune organs (such as the thymus, spleen, and lymph nodes), changes in immune cell number and function, and altered cytokine production. Immunotoxicity probably results from cell death following apoptosis and necrosis, in combination with slow replacement of affected immune cells due to inhibition of protein synthesis. For research purposes only Structure of ochratoxin A
抗原
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