The antibody AGR3.1 recognizes the epitope HETTDKNLS within the AGR3 (AG3) protein (19-20 kDa), a secreted cytoplasmic protein which can serve as a marker of carcinogenesis.
AGR3
适用: 人
IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 680
应用备注
Immunohistochemistry (paraffin sections): Recommended dilution: 1 μg/mL, positive tissue: breast cancer. Immunohistochemistry (frozen sections): Recommended dilution: 1 μg/mL, positive tissue: breast cancer. Western blotting: Recommended dilution: 1 μg/mL, positive control: T47D breast cancer cell line, negative control: H1299 lung carcinoma cell line. Immunocytochemistry: Recommended dilution: 1 μg/mL, positive control: T47D breast cancer cell line, negative control: H1299 lung carcinoma cell line.
限制
仅限研究用
浓度
1 mg/mL
缓冲液
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Do not freeze.
储存条件
4 °C
储存方法
Store at 2-8°C. Do not freeze.
抗原
AGR3
(Anterior Gradient 3 (AGR3))
别名
AGR3
背景
Anterior gradient 3, protein disulphide isomerase,AGR3 (Anterior Gradient 3) protein, also known as AG3 (hAG-3, HAG3 in human), or BCMP11, is a secreted cytoplasmic protein which is involved in metastasis induction and p53 tumour supressor inhibition. It may serve as molecular marker and potential therapeutic target for hormone-responsive breast tumours. Its Xenopus homolog is associated with anteroposterior fate determination during early development.,AG3, HAG3