Progesterone Receptor 抗体 (C-Term)
Quick Overview for Progesterone Receptor 抗体 (C-Term) (ABIN342255)
抗原
See all Progesterone Receptor (PGR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Recognizes human progesterone receptor (PgR), a member of the steroid family of nuclear receptors. PgR is found as a 94 kD protein (Form A) or a 120 kD protein (Form B). Binding of progesterone to its receptor results in a conformational change that allows dimerization and binding of the receptor to progesterone response elements and activated transcription. When bound to DNA, PgR can positively or negatively regulate gene transcription.
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纯化方法
- Protein G purified
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免疫原
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6-His fusion protein containing the region encoding aa 1-101 of human progesterone receptor expressed in E. coli.
Type of Immunogen: Fusion protein -
亚型
- IgG2a
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应用备注
- Approved: WB (1 - 5 μg/mL)
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说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.4
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注意事项
- Avoid freeze/thaw cycles.
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储存条件
- -80 °C
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储存方法
- Store at -70°C, avoid freeze/thaw cycles.
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- Progesterone Receptor (PGR)
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别名
- PGR/PR/Progesterone Receptor
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背景
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Name/Gene ID: PGR
Subfamily: NR3 Steroid receptor
Family: NHR
Synonyms: PGR, NR3C3, PR, Progesterone receptor -
基因ID
- 5241
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UniProt
- P06401
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途径
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration
抗原
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