TPSAB1 抗体
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北京 101111
Quick Overview for TPSAB1 抗体 (ABIN337075)
抗原
See all TPSAB1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes human mast cell tryptase, both isoforms. Is an excellent marker for mast cells, and does not bind to any other cell type in immunohistology. Tryptases are the products of a number of and form the major neutral protease present in mast cells secreted in response to infection and injury. Mast cell tryptase has an important role in the pathology of inflammatory diseases, especially asthma through bronchoconstriction.
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纯化方法
- Protein G purified
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免疫原
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Human mast cell tryptase purified from human lung tissue.
Type of Immunogen: Purified protein -
亚型
- IgG1
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应用备注
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Approved: ELISA, IHC, IHC-Fr, IHC-P (2.5 μg/mL), WB
Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 2.5 μg/mL. Histology Positive Control Tissue: Tonsil. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.4, 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing. Store undiluted.
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储存条件
- 4 °C,-20 °C
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储存方法
- 4°C or -20°C, Avoid freeze-thaw cycles. Store undiluted.
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- TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))
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别名
- TPSAB1 / Mast Cell Tryptase
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背景
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Name/Gene ID: TPSAB1
Subfamily: Serine S1
Family: Protease
Synonyms: TPSAB1, Alpha tryptase, Mast cell alpha II tryptase, Tryptase alpha-1, Tryptase beta I, Tryptase-III, TPSB1, Tryptase alpha II, TPS1, TPS2, Tryptase beta-1, Tryptase-1, Tryptase-I, Mast cell beta I tryptase, Tryptase alpha/beta 1, Tryptase alpha/beta-1, Tryptase beta 1, Tryptase I -
基因ID
- 7177
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UniProt
- Q15661
抗原
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