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TPSAB1 抗体

This 小鼠 单克隆 antibody specifically detects TPSAB1 in WB, IHC, ELISA, IHC (p) 和 IHC (fro). It exhibits reactivity toward 人, 大鼠, 犬, Cat 和 猴.
产品编号 ABIN337075
发货至: 中国
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Quick Overview for TPSAB1 抗体 (ABIN337075)

抗原

See all TPSAB1 抗体
TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))

适用

  • 72
  • 34
  • 17
  • 9
  • 4
  • 2
  • 2
  • 1
人, 大鼠, 犬, Cat, 猴

宿主

  • 73
  • 38
  • 2
  • 1
  • 1
小鼠

克隆类型

  • 75
  • 40
单克隆

标记

  • 65
  • 19
  • 7
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TPSAB1 antibody is un-conjugated

应用范围

  • 79
  • 55
  • 36
  • 16
  • 14
  • 14
  • 10
  • 8
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

AA1
  • 特异性

    Recognizes human mast cell tryptase, both isoforms. Is an excellent marker for mast cells, and does not bind to any other cell type in immunohistology. Tryptases are the products of a number of and form the major neutral protease present in mast cells secreted in response to infection and injury. Mast cell tryptase has an important role in the pathology of inflammatory diseases, especially asthma through bronchoconstriction.

    纯化方法

    Protein G purified

    免疫原

    Human mast cell tryptase purified from human lung tissue.

    Type of Immunogen: Purified protein

    亚型

    IgG1
  • 应用备注

    Approved: ELISA, IHC, IHC-Fr, IHC-P (2.5 μg/mL), WB

    Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 2.5 μg/mL. Histology Positive Control Tissue: Tonsil.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    PBS,  pH 7.4, 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing. Store undiluted.

    储存条件

    4 °C,-20 °C

    储存方法

    4°C or -20°C, Avoid freeze-thaw cycles. Store undiluted.
  • 抗原

    TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))

    别名

    TPSAB1 / Mast Cell Tryptase

    背景

    Name/Gene ID: TPSAB1
    Subfamily: Serine S1
    Family: Protease

    Synonyms: TPSAB1, Alpha tryptase, Mast cell alpha II tryptase, Tryptase alpha-1, Tryptase beta I, Tryptase-III, TPSB1, Tryptase alpha II, TPS1, TPS2, Tryptase beta-1, Tryptase-1, Tryptase-I, Mast cell beta I tryptase, Tryptase alpha/beta 1, Tryptase alpha/beta-1, Tryptase beta 1, Tryptase I

    基因ID

    7177

    UniProt

    Q15661
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