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S100A1 抗体

S100A1 适用: 人, 小鼠, 大鼠, Cow, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN336962
发货至: 中国
  • 抗原 See all S100A1 抗体
    S100A1 (S100 Calcium Binding Protein A1 (S100A1))
    适用
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    人, 小鼠, 大鼠, Cow, 猴
    宿主
    • 68
    • 22
    • 2
    克隆类型
    • 61
    • 32
    多克隆
    标记
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    This S100A1 antibody is un-conjugated
    应用范围
    • 58
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    Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    Molecular Weight: ~22 kDa.
    免疫原
    Purified S100 protein
    Top Product
    Discover our top product S100A1 Primary Antibody
  • 应用备注
    IHC, ICC (frozen or formalin–fixed paraffin-embedded (FFPE) tissue sections, cell smears) 1:50-1:200 using streptavidin-Biotin system or polymer system. Prediluted antibody is used directly without dilution. The optimum dilution should be determined by the individual lab. Cellular Localization: Cytoplasmic.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    :Immunized serum in10 mM PO4, 150 mM NaCl, pH 7.4, 0.05% sodium azide. HostRabbit Intended Use Immunohistochemistry (IHC) and Immunocytchemistry (ICC)
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • 抗原
    S100A1 (S100 Calcium Binding Protein A1 (S100A1))
    别名
    S100 (S100A1 产品)
    别名
    S100 antibody, S100-alpha antibody, S100A antibody, S100A1 antibody, DKFZp468K0511 antibody, AI266795 antibody, S100a antibody, S100 calcium binding protein A1 antibody, S100A1 antibody, S100a1 antibody, s100a1 antibody
    背景
    S100 protein is a type of low molecular weight protein found in vertebrates characterized by two calcium binding sites of the helix-loop-helix (EF-hand type) conformation. There are at least 21 different types of S100 proteins. The name is derived from the fact that the protein is 100% Soluble in ammonium sulfate at neutral pH. Most S100 proteins are homodimeric, consisting of two identical polypeptides held together by non-covalent bonds. S100A is composed of an alpha and beta chain whereas S100B is composed of two beta chains. Although S100 proteins are structurally similar to calmodulin, they differ in that they are cell-specific, expressed in particular cells at different levels depending on environmental factors. To contrast, calmodulin is a ubiquitous and universal intracellular Ca++ receptor widely expressed in many cells.S-100 is normally present in cells derived from the neural crest (Schwann cells, melanocytes, and glia cells), chondrocyte, adipocytes, myoepithelial cells, macrophages, Langerhans cells, dendritic cells, and keratinocytes. It may be present in some breast epithelial cells. This antibody stains schwannoma, ependymomas, astrogliomas, almost all benign and malignant melanoma and their metasis.
    途径
    Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades, S100 Proteins
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