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Cofilin 抗体 (N-Term)

The 小鼠 单克隆 anti-Cofilin antibody (Clone AT1C1) (ABIN336102) specifically detects Cofilin in WB, IHC (p) 和 EIA. The antibody is reactive with 人 samples.
产品编号 ABIN336102
发货至: 中国
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Quick Overview for Cofilin 抗体 (N-Term) (ABIN336102)

抗原

See all Cofilin (CFL1) 抗体
Cofilin (CFL1) (Cofilin 1 (CFL1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Cofilin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

克隆位点

AT1C1
  • 抗原表位

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    AA 1-166, N-Term

    特异性

    The antibody recognizes Human Cofilin-1. Other species not tested.

    产品特性

    Synonyms: CFL1, CFL, p18, Cofilin non-muscle isoform, 18 kDa phosphoprotein

    纯化方法

    Protein-G affinity chromatography

    免疫原

    Recombinant human Cofilin-1 (aa 1-166) purified from E. coli

    亚型

    IgG1
  • 应用备注

    ELISA. Western blot (1/1,000-1/2,000). Immunohistochemistry on Paraffin Sections (10 μg/mL). This Cofilin 1 antibody was validated for use in immunohistochemistry on a panel of 21formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigenretrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides wereincubated with biotinylated secondary antibody, followed by alkalinephosphatase-streptavidin and chromogen.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C or -70 °Cfor longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    Cofilin (CFL1) (Cofilin 1 (CFL1))

    别名

    Cofilin-1

    背景

    Cofilin is a family of actin-binding proteins which disassembles actin filaments. It is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH -dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.Synonyms: 18 kDa phosphoprotein, CFL, CFL1, Cofilin non-muscle isoform, p18

    基因ID

    1072

    UniProt

    P23528

    途径

    Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events
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