我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

HNE 抗体

Name: HNE 抗体
Brand: antibodies-online
SKU: ABIN335414
Availability: OutOfStock

Cited in 31+ publications. This anti-HNE antibody is a 小鼠单克隆 antibody detecting HNE in WB, ELISA 和 IHC. Suitable for not_set.

Image no. 1 for anti-4-Hydroxynonenal (HNE) antibody (ABIN335414) (HNE 抗体)

1 image

(31 references)

产品编号 ABIN335414

发货至: 中国

Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111

No. 88 KeChuang 6th Street

Beijing Economic Technological Development Area

Room 801-803

4A Biotech Co.,Ltd.

Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for HNE 抗体 (ABIN335414)

抗原

See all HNE 抗体

HNE (4-Hydroxynonenal (HNE))

适用

请咨询

宿主

小鼠

克隆类型

单克隆

标记

This HNE antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

克隆位点

HNEJ-2

Discover our top product HNE Primary Antibody

特异性

Specific for 4HNE-Lysine, 4-HNE-histidine and 4-HNE cysteine adduct.By inhibition test, this antibody has a much higher affinity for the 4-HNE-histidine adduct than 4-HNE-lysine or 4-HNE cysteine adduct. This antibody show almost negligible reactivity with proteins that were treated with other aldehydes, such as 2-nonenal, 2-hexenal, 1-hexanal, 4-hydroxy-2-hexenal, formaldehyde, or glutaraldehyde. By inhibition test, this antibody shows a much higher affinity for the 4-HNE-histidine adduct than 4-HNE-lysine or 4-HNE-cysteine adduct.

纯化方法

Ammonium sulphate purified IgG

免疫原

4-Hydroxy-2-nonenal (4HNE) modified keyhole limpet hemocyanin.

亚型

IgG1 kappa
anti-4-Hydroxynonenal (HNE) antibody
HNE WB, ELISA, IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-4-Hydroxynonenal (HNE) antibody
HNE WB, ELISA, ICC, IF 宿主: 小鼠 Monoclonal 12F7 unconjugated

anti-4-Hydroxynonenal (HNE) antibody (HRP)
HNE WB, ELISA, ICC, IF 宿主: 小鼠 Monoclonal 12F7 HRP

anti-4-Hydroxynonenal (HNE) antibody (FITC)
HNE WB, ELISA, ICC, IF 宿主: 小鼠 Monoclonal 12F7 FITC

anti-4-Hydroxynonenal (HNE) antibody (Biotin)
HNE WB, ELISA, ICC, IF 宿主: 小鼠 Monoclonal 12F7 Biotin

anti-4-Hydroxynonenal (HNE) antibody (PE)
HNE WB, ELISA, ICC, IF 宿主: 小鼠 Monoclonal 12F7 PE

anti-4-Hydroxynonenal (HNE) antibody (PerCP)
HNE WB, ELISA, ICC, IF 宿主: 小鼠 Monoclonal 12F7 PerCP

anti-4-Hydroxynonenal (HNE) antibody (APC)
HNE WB, ELISA, ICC, IF 宿主: 小鼠 Monoclonal 12F7 APC

anti-4-Hydroxynonenal (HNE) antibody (Atto 594)
HNE WB, ELISA, ICC, IF 宿主: 小鼠 Monoclonal 12F7 Atto 594

anti-4-Hydroxynonenal (HNE) antibody (Atto 488)
HNE WB, ELISA, ICC, IF 宿主: 小鼠 Monoclonal 12F7 Atto 488

应用备注

Immunohistochemistry [ref.1] (Recommended concentration: 25 ug/mL IgG). Western blotting [ref.2] (Recommended concentration: 15 ug/mL IgG) User should determine optimum titer for each application.

限制

仅限研究用
状态

Lyophilized

溶解方式

Reconstitute with 1000μL of distilled water.

缓冲液

100ug/mL IgG in 50 mM Tris buffered saline (TBS).

储存条件

-20 °C
Miyake, Tanabe, Tanimura, Nakashima, Morioka, Masuda, Sugiyama, Sato, Wada: "Genetic Deletion of Vasohibin-2 Exacerbates Ischemia-Reperfusion-Induced Acute Kidney Injury." in: International journal of molecular sciences, Vol. 21, Issue 12, (2020) (PubMed).

Kanbara, Ohkawara, Nakashima, Ohta, Koshimizu, Inoue, Tomita, Ito, Masuda, Ishiguro, Imagama, Ohno: "Zonisamide ameliorates progression of cervical spondylotic myelopathy in a rat model." in: Scientific reports, Vol. 10, Issue 1, pp. 13138, (2020) (PubMed).

Hosohata, Jin, Takai, Iwanaga: "Vanin-1 in Renal Pelvic Urine Reflects Kidney Injury in a Rat Model of Hydronephrosis." in: International journal of molecular sciences, Vol. 19, Issue 10, (2019) (PubMed).

Paka, Smith, Jung, McCormack, Zhou, Duan, Li, Shi, Hao, Jiang, Yamin, Goldberg, Narayan: "Anti-steatotic and anti-fibrotic effects of the KCa3.1 channel inhibitor, Senicapoc, in non-alcoholic liver disease." in: World journal of gastroenterology, Vol. 23, Issue 23, pp. 4181-4190, (2018) (PubMed).

Uneda, Wakui, Maeda, Azushima, Kobayashi, Haku, Ohki, Haruhara, Kinguchi, Matsuda, Ohsawa, Minegishi, Ishigami, Toya, Atobe, Yamashita, Umemura, Tamura: "Angiotensin II Type 1 Receptor-Associated Protein Regulates Kidney Aging and Lifespan Independent of Angiotensin." in: Journal of the American Heart Association, Vol. 6, Issue 8, (2018) (PubMed).

Uetake, Ikeda, Irie, Tejima, Matsui, Ogura, Wang, Mu, Hirohama, Ando, Sawamura, Yatomi, Fujita, Shimosawa: "High-salt in addition to high-fat diet may enhance inflammation and fibrosis in liver steatosis induced by oxidative stress and dyslipidemia in mice." in: Lipids in health and disease, Vol. 14, pp. 6, (2016) (PubMed).

Miller, Singh, Wang, Hall: "Nrf2-ARE activator carnosic acid decreases mitochondrial dysfunction, oxidative damage and neuronal cytoskeletal degradation following traumatic brain injury in mice." in: Experimental neurology, Vol. 264, pp. 103-10, (2015) (PubMed).

Apidianakis, Que, Xu, Tegos, Zimniak, Hamblin, Tompkins, Xiao, Rahme: "Down-regulation of glutatione S-transferase α 4 (hGSTA4) in the muscle of thermally injured patients is indicative of susceptibility to bacterial infection." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 26, Issue 2, pp. 730-7, (2012) (PubMed).

Tskitishvili, Sharentuya, Temma-Asano, Mimura, Kinugasa-Taniguchi, Kanagawa, Fukuda, Kimura, Tomimatsu, Shimoya: "Oxidative stress-induced S100B protein from placenta and amnion affects soluble Endoglin release from endothelial cells." in: Molecular human reproduction, Vol. 16, Issue 3, pp. 188-99, (2010) (PubMed).

Ogawa, Fujii, Yoshizato, Kawada: "A human-type nonalcoholic steatohepatitis model with advanced fibrosis in rabbits." in: The American journal of pathology, Vol. 177, Issue 1, pp. 153-65, (2010) (PubMed).

Wakamatsu, Dogru, Ayako, Takano, Matsumoto, Ibrahim, Okada, Satake, Fukagawa, Shimazaki, Tsubota, Fujishima: "Evaluation of lipid oxidative stress status and inflammation in atopic ocular surface disease." in: Molecular vision, Vol. 16, pp. 2465-75, (2010) (PubMed).

Raz, Zhang, Zhou, Han, Gulati, Yang, Yang, Wang, Brann: "Role of Rac1 GTPase in NADPH oxidase activation and cognitive impairment following cerebral ischemia in the rat." in: PLoS ONE, Vol. 5, Issue 9, pp. e12606, (2010) (PubMed).

Kurashige, Abe, Furusu, Miyazaki, Obata, Xia, Nakazawa, Nakazawa, Funakoshi, Harada, Koji, Kohno: "Renoprotective effect of azelnidipine in rats." in: Biological & pharmaceutical bulletin, Vol. 31, Issue 12, pp. 2237-44, (2008) (PubMed).

Amidi, French, Chung, Halsted, Medici, French: "M-30 and 4HNE are sequestered in different aggresomes in the same hepatocytes." in: Experimental and molecular pathology, Vol. 83, Issue 3, pp. 296-300, (2007) (PubMed).

Kodai, Takemura, Minamiyama, Hai, Yamamoto, Kubo, Yoshida, Niki, Okada, Hirohashi, Suehiro: "S-allyl cysteine prevents CCl(4)-induced acute liver injury in rats." in: Free radical research, Vol. 41, Issue 4, pp. 489-97, (2007) (PubMed).

Tanito, Kaidzu, Anderson: "Delayed loss of cone and remaining rod photoreceptor cells due to impairment of choroidal circulation after acute light exposure in rats." in: Investigative ophthalmology & visual science, Vol. 48, Issue 4, pp. 1864-72, (2007) (PubMed).

Kurimoto, Kawano, Tsuji, Hatachi, Jikimoto, Sugiyama, Kasagi, Komori, Nakamura, Yodoi, Kumagai: "Thioredoxin may exert a protective effect against tissue damage caused by oxidative stress in salivary glands of patients with Sjögren's syndrome." in: The Journal of rheumatology, Vol. 34, Issue 10, pp. 2035-43, (2007) (PubMed).

Hirono, Yoshimoto, Suzuki, Sugiyama, Sakurada, Takai, Kobayashi, Shichiri, Hirata: "Angiotensin II receptor type 1-mediated vascular oxidative stress and proinflammatory gene expression in aldosterone-induced hypertension: the possible role of local renin-angiotensin system." in: Endocrinology, Vol. 148, Issue 4, pp. 1688-96, (2007) (PubMed).

Choi, Ryu, Kim, McLarnon: "Modulation of the purinergic P2X7 receptor attenuates lipopolysaccharide-mediated microglial activation and neuronal damage in inflamed brain." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 18, pp. 4957-68, (2007) (PubMed).

Tanito, Elliott, Kotake, Anderson: "Protein modifications by 4-hydroxynonenal and 4-hydroxyhexenal in light-exposed rat retina." in: Investigative ophthalmology & visual science, Vol. 46, Issue 10, pp. 3859-68, (2005) (PubMed).

show more references
抗原

HNE (4-Hydroxynonenal (HNE))

物质类

Chemical