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GFAP 抗体

GFAP 适用: 人, 大鼠, 小鼠, 斑马鱼 WB, IHC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal K39 unconjugated
产品编号 ABIN335275
发货至: 中国
  • 抗原 See all GFAP 抗体
    GFAP (Glial Fibrillary Acidic Protein (GFAP))
    适用
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    人, 大鼠, 小鼠, 斑马鱼
    宿主
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    克隆类型
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    多克隆
    标记
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    This GFAP antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    Human, mouse and rat.
    纯化方法
    Antiserum
    免疫原
    K39 is a rabbit polyclonal antiserum derived by immunization of a rabbit with a glial fibrillary acidic protein preparation from human spinal cord.
    克隆位点
    K39
    Top Product
    Discover our top product GFAP Primary Antibody
  • 应用备注
    K39 reacts exclusively with glial fibrillary acidic protein which is present in astrocytes in the central nervous system and Schwann cells. K39 is suitable for immunoblotting and immunohistochemistry on frozen and paraffin-embedded tissues. Optimal antibody dilution should be determined by titration, recommended range is 1:100 - 1:200 for immunohistochemistry with avidin-biotinylated horseradish peroxidase complex (ABC) as detection reagent, and 1:100 - 1:1000 for immunoblotting applications.
    限制
    仅限研究用
  • 状态
    Liquid
    储存条件
    4 °C
  • Herpers, Ramaekers, Aldeweireldt, Moesker, Slooff: "Co-expression of glial fibrillary acidic protein- and vimentin-type intermediate filaments in human astrocytomas." in: Acta neuropathologica, Vol. 70, Issue 3-4, pp. 333-9, (1986) (PubMed).

    Ramaekers, Puts, Moesker, Kant, Huysmans, Haag, Jap, Herman, Vooijs: "Antibodies to intermediate filament proteins in the immunohistochemical identification of human tumours: an overview." in: The Histochemical journal, Vol. 15, Issue 7, pp. 691-713, (1983) (PubMed).

  • 抗原
    GFAP (Glial Fibrillary Acidic Protein (GFAP))
    别名
    Glial fibrillary acidic protein / GFAP (GFAP 产品)
    别名
    GFAP antibody, AI836096 antibody, cb345 antibody, etID36982.3 antibody, gfapl antibody, wu:fb34h11 antibody, wu:fk42c12 antibody, xx:af506734 antibody, zgc:110485 antibody, glial fibrillary acidic protein antibody, GFAP antibody, LOC100136168 antibody, gfap antibody, Gfap antibody
    背景
    GFAP (55 kD) is selectively located in astrocytes and represents the major constituent of astrocytic intermediate filaments. GFAP expression levels are highly variable during development of the central nervous system. In adults, GFAP levels increase as a result of the proliferation of astrocytes that occurs in a response to a variety of physical, chemical and etiological insults, including Alzheimer€™s disease, epilepsy and multiple sclerosis. In the peripheral nervous system GFAP is expressed by Schwann cells. Upon differentiation, myelin forming Schwann cells down-regulate GFAP, whereas in non-myelin forming Schwann cells GFAP persists into adulthood.
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