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Toxin B 抗体

This 小鼠 单克隆 antibody specifically detects Toxin B in ELISA 和 WB. It exhibits reactivity toward Clostridium difficile. It has been mentioned in 7+ publications
产品编号 ABIN335173
发货至: 中国
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Quick Overview for Toxin B 抗体 (ABIN335173)

抗原

Toxin B

适用

Clostridium difficile

宿主

  • 6
  • 2
  • 2
  • 2
小鼠

克隆类型

  • 8
  • 2
单克隆

标记

  • 11
  • 1
非结合性

应用范围

  • 4
  • 3
  • 1
ELISA, Western Blotting (WB)
  • 特异性

    Antibody recognises TcdB in general

    纯化方法

    The antibody was purified by protein A from cell culture supernatants and is routinely tested

    免疫原

    was generated by immunisation of mice with toxin and toxin fragments
  • 限制

    仅限研究用
  • 浓度

    1 mg/ml

    缓冲液

    PBS

    储存条件

    4 °C
  • Quesada-Gómez, López-Ureña, Chumbler, Kroh, Castro-Peña, Rodríguez, Orozco-Aguilar, González-Camacho, Rucavado, Guzmán-Verri, Lawley, Lacy, Chaves-Olarte: "Analysis of TcdB Proteins within the Hypervirulent Clade 2 Reveals an Impact of RhoA Glucosylation on Clostridium difficile Proinflammatory Activities." in: Infection and immunity, Vol. 84, Issue 3, pp. 856-65, (2016) (PubMed).

    Costa, López-Ureña, de Oliveira Assis, Ribeiro, Silva, Rupnik, Wilcox, de Carvalho, do Carmo, Dias, de Carvalho, Chaves-Olarte, Rodríguez, Quesada-Gómez, de Castro Brito: "A MLST Clade 2 Clostridium difficile strain with a variant TcdB induces severe inflammatory and oxidative response associated with mucosal disruption." in: Anaerobe, Vol. 40, pp. 76-84, (2016) (PubMed).

    Quesada-Gómez, López-Ureña, Acuña-Amador, Villalobos-Zúñiga, Du, Freire, Guzmán-Verri, del Mar Gamboa-Coronado, Lawley, Moreno, Mulvey, de Castro Brito, Rodríguez-Cavallini, Rodríguez, Chaves-Olarte: "Emergence of an outbreak-associated Clostridium difficile variant with increased virulence." in: Journal of clinical microbiology, Vol. 53, Issue 4, pp. 1216-26, (2015) (PubMed).

    Wullt, Norén, Ljungh, Åkerlund: "IgG antibody response to toxins A and B in patients with Clostridium difficile infection." in: Clinical and vaccine immunology : CVI, Vol. 19, Issue 9, pp. 1552-4, (2012) (PubMed).

    Kuehne, Cartman, Heap, Kelly, Cockayne, Minton: "The role of toxin A and toxin B in Clostridium difficile infection." in: Nature, Vol. 467, Issue 7316, pp. 711-3, (2010) (PubMed).

    Reineke, Tenzer, Rupnik, Koschinski, Hasselmayer, Schrattenholz, Schild, von Eichel-Streiber: "Autocatalytic cleavage of Clostridium difficile toxin B." in: Nature, Vol. 446, Issue 7134, pp. 415-9, (2007) (PubMed).

    Rupnik, Pabst, Rupnik, von Eichel-Streiber, Urlaub, Söling: "Characterization of the cleavage site and function of resulting cleavage fragments after limited proteolysis of Clostridium difficile toxin B (TcdB) by host cells." in: Microbiology (Reading, England), Vol. 151, Issue Pt 1, pp. 199-208, (2005) (PubMed).

  • 抗原

    Toxin B
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