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Toxin A 抗体

Cited in 6+ publications. The 小鼠 单克隆 anti-Toxin A antibody (ABIN335169) specifically detects Toxin A in ELISA 和 WB. The antibody is reactive with Clostridium difficile samples.
产品编号 ABIN335169
发货至: 中国
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Quick Overview for Toxin A 抗体 (ABIN335169)

抗原

Toxin A

适用

  • 8
  • 2
Clostridium difficile

宿主

  • 3
  • 3
  • 2
  • 2
小鼠

克隆类型

  • 5
  • 3
单克隆

标记

  • 9
  • 1
非结合性

应用范围

  • 7
  • 3
  • 2
  • 1
ELISA, Western Blotting (WB)
  • 特异性

    Antibody recognises TcdA in general

    纯化方法

    The antibody was purified by protein A from cell culture supernatants and is routinely tested

    免疫原

    was generated by immunisation of mice with toxin and toxin fragments
  • 限制

    仅限研究用
  • 浓度

    3 mg/ml

    缓冲液

    PBS

    储存条件

    4 °C
  • Leslie, Vendrov, Jenior, Young: "The Gut Microbiota Is Associated with Clearance of Clostridium difficile Infection Independent of Adaptive Immunity." in: mSphere, Vol. 4, Issue 1, (2019) (PubMed).

    Quesada-Gómez, López-Ureña, Chumbler, Kroh, Castro-Peña, Rodríguez, Orozco-Aguilar, González-Camacho, Rucavado, Guzmán-Verri, Lawley, Lacy, Chaves-Olarte: "Analysis of TcdB Proteins within the Hypervirulent Clade 2 Reveals an Impact of RhoA Glucosylation on Clostridium difficile Proinflammatory Activities." in: Infection and immunity, Vol. 84, Issue 3, pp. 856-65, (2016) (PubMed).

    Costa, López-Ureña, de Oliveira Assis, Ribeiro, Silva, Rupnik, Wilcox, de Carvalho, do Carmo, Dias, de Carvalho, Chaves-Olarte, Rodríguez, Quesada-Gómez, de Castro Brito: "A MLST Clade 2 Clostridium difficile strain with a variant TcdB induces severe inflammatory and oxidative response associated with mucosal disruption." in: Anaerobe, Vol. 40, pp. 76-84, (2016) (PubMed).

    Quesada-Gómez, López-Ureña, Acuña-Amador, Villalobos-Zúñiga, Du, Freire, Guzmán-Verri, del Mar Gamboa-Coronado, Lawley, Moreno, Mulvey, de Castro Brito, Rodríguez-Cavallini, Rodríguez, Chaves-Olarte: "Emergence of an outbreak-associated Clostridium difficile variant with increased virulence." in: Journal of clinical microbiology, Vol. 53, Issue 4, pp. 1216-26, (2015) (PubMed).

    Wullt, Norén, Ljungh, Åkerlund: "IgG antibody response to toxins A and B in patients with Clostridium difficile infection." in: Clinical and vaccine immunology : CVI, Vol. 19, Issue 9, pp. 1552-4, (2012) (PubMed).

    Kuehne, Cartman, Heap, Kelly, Cockayne, Minton: "The role of toxin A and toxin B in Clostridium difficile infection." in: Nature, Vol. 467, Issue 7316, pp. 711-3, (2010) (PubMed).

  • 抗原

    Toxin A
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