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Fascin 2 抗体 (Internal Region)

This anti-Fascin 2 antibody is a 山羊 多克隆 antibody detecting Fascin 2 in IHC 和 ELISA. Suitable for 小鼠. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN334397
发货至: 中国

Quick Overview for Fascin 2 抗体 (Internal Region) (ABIN334397)

抗原

See all Fascin 2 (FSCN2) 抗体
Fascin 2 (FSCN2)

适用

  • 18
  • 17
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
小鼠

宿主

  • 30
  • 1
山羊

克隆类型

  • 31
多克隆

标记

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  • 10
  • 3
  • 1
This Fascin 2 antibody is un-conjugated

应用范围

  • 25
  • 13
  • 10
  • 7
  • 6
  • 2
Immunohistochemistry (IHC), ELISA

质量等级

Verified
  • 抗原表位

    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region

    原理

    Fascin 2

    序列

    CHHRGSNQLD TNR

    特异性

    This antibody is expected to recognize both reported isoforms (NP_001070650.1 and NP_036550.1).

    交叉反应

    犬, 人, 小鼠, 大鼠

    纯化方法

    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

    免疫原

    Peptide with sequence CHHRGSNQLDTNR, from the internal region of the protein sequence according to NP_001070650.1, NP_036550.1.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry: Paraffin embedded Mouse Brain. Recommended concentration: 4 μg/mL. This product was successfully used on sections of mouse cochlea as descibed in Shin et al, J Neurosci. 2010 Jul 21,30(29):9683-94, PMID: 20660251.

    Peptide ELISA: antibody detection limit dilution 1:64000.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Minimize freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
  • Burns, Kelly, Hoa, Morell, Kelley: "Single-cell RNA-Seq resolves cellular complexity in sensory organs from the neonatal inner ear." in: Nature communications, Vol. 6, pp. 8557, (2015) (PubMed).

    Ramakrishnan, Drescher, Khan, Hatfield, Drescher: "HCN1 and HCN2 proteins are expressed in cochlear hair cells: HCN1 can form a ternary complex with protocadherin 15 CD3 and F-actin-binding filamin A or can interact with HCN2." in: The Journal of biological chemistry, Vol. 287, Issue 45, pp. 37628-46, (2012) (PubMed).

    Shin, Longo-Guess, Gagnon, Saylor, Dumont, Spinelli, Pagana, Wilmarth, David, Gillespie, Johnson: "The R109H variant of fascin-2, a developmentally regulated actin crosslinker in hair-cell stereocilia, underlies early-onset hearing loss of DBA/2J mice." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 29, pp. 9683-94, (2010) (PubMed).

  • 抗原

    Fascin 2 (FSCN2)

    别名

    FSCN2

    背景

    Fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus), RFSN, RP30, fascin 2, retinal fascin,

    基因ID

    25794, 238021, 303741

    NCBI登录号

    NP_001070650, NP_036550
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