C4BP 抗体
The 小鼠 单克隆 anti-C4BP antibody is suitable to detect C4BP in samples from 人. It has been validated for ELISA, IHC (p) 和 IHC.
产品编号 ABIN334259
发货至:
中国
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Quick Overview for C4BP 抗体 (ABIN334259)
抗原
C4BP
(C4b-Binding Protein)
适用
人
宿主
小鼠
克隆类型
单克隆
标记
This C4BP antibody is un-conjugated
应用范围
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC)
克隆位点
10-07
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特异性
- Recognizes complement component 4 binding protein (C4bp). There are three variants of C4bp, composed of alpha and beta chains. The predominant form is a 570 kD complex of 7 alpha chains and 1 beta chain. The other complexes formed are a 530 kD homoheptamer of alpha chains or a 500 kD complex of 6 alpha chains and 1 beta chain. C4bp regulates the activation of the classical complement pathway. It is a cofactor to the C3b/C4b inactivator, crucial to the proteolytic cleavage of C4b and important in cleavage of C3b. C4bp also regulates the C4bC2a complex (C3 convertase), accelerating its degradation by dissociating the complement fragment C2a. Both the C4bp alpha and beta chains interact with anticoagulant protein S and C4bp alpha binds protein S. C4bp is expressed in the blood serum.
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纯化方法
- Protein A purified from ascites
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免疫原
- Native human C4 binding protein.
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亚型
- IgG2b
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anti-C4b-Binding Protein antibody
适用: 人 IHC (p), ID 宿主: 绵羊 Polyclonal unconjugated
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应用备注
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Approved: ELISA, IHC, IHC-P (5 μg/mL)
Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Borate buffered saline, 0.1 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing. Store undiluted.
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储存条件
- 4 °C,-20 °C
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储存方法
- 4°C or -20°C, Avoid freeze-thaw cycles. Store undiluted.
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- C4BP (C4b-Binding Protein)
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别名
- C4BP / C4b-Binding Protein
抗原
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