beta-2 Microglobulin 抗体
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Quick Overview for beta-2 Microglobulin 抗体 (ABIN334257)
抗原
See all beta-2 Microglobulin (B2M) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes native human beta 2 microglobulin, a 119 amino acid component of MHC class I molecules present on all nucleated cells, containing a single domain, Levels of beta 2 microglobulin can be used to assess renal function in kidney transplant recipients. Also known as B2M, it has been suggested that this protein can be used as a prognostic marker for HIV infection.
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纯化方法
- Protein A purified
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免疫原
- Highly pure beta-2-microglobulin from human urine.
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亚型
- IgG1
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应用备注
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Approved: ELISA, IHC, IHC-P (5 μg/mL)
Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, pH 8.0, 0.05 % sodium azide, 10 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
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别名
- B2M / Beta 2 Microglobulin
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背景
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Name/Gene ID: B2M
Synonyms: B2M, Beta 2 Microglobulin, Beta-2-microglobulin, Beta-2-microglobin -
基因ID
- 567
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UniProt
- P61769
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途径
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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