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beta-2 Microglobulin 抗体

The 小鼠 单克隆 anti-beta-2 Microglobulin antibody (Clone 2213) (ABIN334257) specifically detects beta-2 Microglobulin in IHC, ELISA 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN334257
发货至: 中国
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Quick Overview for beta-2 Microglobulin 抗体 (ABIN334257)

抗原

See all beta-2 Microglobulin (B2M) 抗体
beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

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小鼠

克隆类型

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单克隆

标记

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This beta-2 Microglobulin antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

2213
  • 特异性

    Recognizes native human beta 2 microglobulin, a 119 amino acid component of MHC class I molecules present on all nucleated cells, containing a single domain, Levels of beta 2 microglobulin can be used to assess renal function in kidney transplant recipients. Also known as B2M, it has been suggested that this protein can be used as a prognostic marker for HIV infection.

    纯化方法

    Protein A purified

    免疫原

    Highly pure beta-2-microglobulin from human urine.

    亚型

    IgG1
  • 应用备注

    Approved: ELISA, IHC, IHC-P (5 μg/mL)

    Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    PBS,  pH 8.0, 0.05 % sodium azide, 10 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    4°C or -20°C, Avoid freeze-thaw cycles.
  • 抗原

    beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

    别名

    B2M / Beta 2 Microglobulin

    背景

    Name/Gene ID: B2M

    Synonyms: B2M, Beta 2 Microglobulin, Beta-2-microglobulin, Beta-2-microglobin

    基因ID

    567

    UniProt

    P61769

    途径

    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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