Lipase A 抗体
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北京 101111
Quick Overview for Lipase A 抗体 (ABIN3210008)
抗原
See all Lipase A (LIPA) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Purified antibody.
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免疫原
- LAL antibody was raised in Mouse using a purified recombinant fragment of LAL expressed in E. coli as the immunogen.
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亚型
- IgG2a
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应用备注
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ELISA: 1:10,000, WB: 1:500-1:2000,
Optimal conditions should be determined by the investigator. -
限制
- 仅限研究用
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浓度
- Lot specific
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缓冲液
- Purified antibody supplied in PBS containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C for short term storage. Store at -20 °C for long term storage.
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- Lipase A (LIPA) (Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA))
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别名
- LAL
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背景
- LAL functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides which are taken up by receptor-mediated endocytosis. An inherited deficiency or low activity of human lysosomal acid lipase results in the intralysosomal storage of the respective lipid substrates. So it is also responsible for the rare conditions of Wolman disease and cholesteryl ester storage disease (CESD). As the enzyme is synthesized by all nucleated cells, lipid-laden cells are found in all organs, particularly in liver, spleen, the adrenal and the hemopoietic system, and in the intestine as well as in the lymph nodes, lungs, testes, and ovaries. Synonyms: Monoclonal LAL antibody, Anti-LAL antibody, Lysosomal acid lipase antibody.
抗原
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