NCR1 抗体
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Quick Overview for NCR1 抗体 (ABIN320238)
抗原
See all NCR1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This Low Endotoxin antibody is specific for Bovine CD335, also known as NKp46 and Natural cytotoxicity triggering receptor 1. Clone AKS1 is reported to activate lysis of FcgammaR-expressing cell line P815, by IL-2 activated NKp46+ cells (2).
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纯化方法
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
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内毒素水平
- Low Endotoxin
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免疫原
- Fusion protein consisting of the extracellular region of Bovine CD335. Remarks: Spleen cells from immunised Balb/c mice were fused with cells of the NS-0 myeloma cell line.
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亚型
- IgG1
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应用备注
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Flow Cytometry: Use 10 μL of 1/5-1/200 diluted antibody to label 106 cells in 100 μL. Western Blot. Functional Assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: Endotoxin Level: < 0.01EU/ug. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.4 containing no preservatives.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
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- NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))
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别名
- CD335 / NKp46
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背景
- CD335 is a type I transmembrane protein, with two extracellular C2-type immunoglobulin-like domains, which functions as an activating receptor. CD335 is expressed by human natural killer cells (4). The bovine homologue is expressed on bovine NK cells (2) and no expression of CD335 has been detected on B cells, T cells, monocytes or granulocytes.Synonyms: LY94, NCR1, NK cell-activating receptor, NKp46, Natural cytotoxicity triggering receptor, Natural killer cell p46-related protei
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基因ID
- 369024
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NCBI登录号
- NP_899209
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UniProt
- Q863H2
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途径
- Regulation of Leukocyte Mediated Immunity
抗原
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