CD13 抗体 (PE)
Our Local Distributor
北京 101111
Quick Overview for CD13 抗体 (PE) (ABIN320068)
抗原
See all CD13 (ANPEP) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- MCA2183PE recognises mouse aminopeptidase N (APN), a cell surface protein homologous with human CD13. In the mouse, CD13 is a non-covalently linked homodimer of approximately 150 kDa subunits expressed by a variety of cells including monocytes, macrophages, dendritic cell and veiled cells. Clone R3-63 has been reported to block mouse APN enzyme activity (1). Serotec recommend the use of MCA2183XZ for this purpose.
-
纯化方法
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
-
免疫原
- Mouse intestinal APN
-
亚型
- IgG2a
-
-
-
-
应用备注
-
Flow Cytometry Neat
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
溶解方式
- Reconstitute in 0.25 mL disilled water
-
浓度
- 0.1 mg/mL
-
缓冲液
- Phosphate buffered saline pH 7.4 0.09 % Sodium Azide, 1 % Bovine Serum Albumin,
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- This product is photosensitive and should be protected from light
-
储存条件
- 4 °C
-
储存方法
- Prior to and following reconstitution store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
-
-
- CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))
-
别名
- CD13
-
背景
- CD13 also known as Aminopeptidase N is a zinc dependent exopeptidase which cleaves amino acids from the N termini of target proteins including neuropeptides and cytokines. CD13 is expressed on all cells of the myeloid lineage as well as epithelial cells of the intestine, placenta, liver and kidney. CD13 is upregulated in a number of tumour types including lung, melanoma, thyroid and hepatocarcinoma and has been shown to correlate with poor prognosis. CD13 is a crucial molecule in tumour angiogenesis. CD13 is also the receptor for viruses from the coronavirus family.Synonyms: ANPEP, APN, Alanyl aminopeptidase, Aminopeptidase M, Aminopeptidase N, Microsomal aminopeptidase, Myeloid plasma membrane glycoprotein CD13, PEPN, gp150
-
基因ID
- 16790
-
NCBI登录号
- NP_032512
-
UniProt
- P97449
-
途径
- Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones
抗原
-