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CD13 抗体 (PE)

ANPEP 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal R3-63 PE
产品编号 ABIN320068
发货至: 中国
  • 抗原 See all CD13 (ANPEP) 抗体
    CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))
    适用
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    小鼠
    宿主
    • 92
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    大鼠
    克隆类型
    • 113
    • 52
    单克隆
    标记
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    This CD13 antibody is conjugated to PE
    应用范围
    • 110
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    Flow Cytometry (FACS)
    特异性
    MCA2183PE recognises mouse aminopeptidase N (APN), a cell surface protein homologous with human CD13. In the mouse, CD13 is a non-covalently linked homodimer of approximately 150 kDa subunits expressed by a variety of cells including monocytes, macrophages, dendritic cell and veiled cells. Clone R3-63 has been reported to block mouse APN enzyme activity (1). Serotec recommend the use of MCA2183XZ for this purpose.
    纯化方法
    Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
    免疫原
    Mouse intestinal APN
    克隆位点
    R3-63
    亚型
    IgG2a
    Top Product
    Discover our top product ANPEP Primary Antibody
  • 应用备注
    Flow Cytometry Neat
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Reconstitute in 0.25 mL disilled water
    浓度
    0.1 mg/mL
    缓冲液
    Phosphate buffered saline pH 7.4 0.09 % Sodium Azide, 1 % Bovine Serum Albumin,
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    This product is photosensitive and should be protected from light
    储存条件
    4 °C
    储存方法
    Prior to and following reconstitution store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
  • 抗原
    CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))
    别名
    CD13 (ANPEP 产品)
    背景
    CD13 also known as Aminopeptidase N is a zinc dependent exopeptidase which cleaves amino acids from the N termini of target proteins including neuropeptides and cytokines. CD13 is expressed on all cells of the myeloid lineage as well as epithelial cells of the intestine, placenta, liver and kidney. CD13 is upregulated in a number of tumour types including lung, melanoma, thyroid and hepatocarcinoma and has been shown to correlate with poor prognosis. CD13 is a crucial molecule in tumour angiogenesis. CD13 is also the receptor for viruses from the coronavirus family.Synonyms: ANPEP, APN, Alanyl aminopeptidase, Aminopeptidase M, Aminopeptidase N, Microsomal aminopeptidase, Myeloid plasma membrane glycoprotein CD13, PEPN, gp150
    基因ID
    16790
    NCBI登录号
    NP_032512
    UniProt
    P97449
    途径
    Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones
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