CD161 抗体
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Quick Overview for CD161 抗体 (ABIN319957)
抗原
See all CD161 (KLRB1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognises the CD161 cell surface antigen. Clone B199.2 recognises a similar epitope to the DX9 monoclonal antibody.
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Affinity Chromatography on Protein G.
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免疫原
- Spleen cells from immunised BALB/c mice were fused with cells of the mouse P2X63.Ag8.653 myeloma cell line.
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亚型
- IgG1
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anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) (AA 73-188) antibody
KLRB1 适用: 人 WB, IP, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) antibodyKLRB1 适用: 人, Non-Human Primate FACS, WB, IHC (fro) 宿主: 小鼠 Monoclonal HP-3G10 unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) antibody (PE)KLRB1 适用: 大鼠 FACS 宿主: 小鼠 Monoclonal 10-78 PE
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) (AA 67-225) antibodyKLRB1 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 4C6A11 unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) (AA 151-225) antibodyKLRB1 适用: 人, 大鼠 ELISA 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) antibodyKLRB1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) antibodyKLRB1 适用: 大鼠 FACS, WB, IP, IHC (fro), RIA 宿主: 小鼠 Monoclonal 10-78 unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) antibody (FITC)KLRB1 适用: 大鼠 FACS 宿主: 小鼠 Monoclonal 10-78 FITC
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) (AA 73-140) antibodyKLRB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) antibodyKLRB1 适用: 大鼠 FACS, WB, IP, IHC (fro), RIA 宿主: 小鼠 Monoclonal 10-78 unconjugated
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应用备注
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Flow Cytometry: Use 10 μL of 1/50-1/100 diluted antibody to label 10^6 cells in 100 μL. Immunoprecipitation. Immunohistochemistry on Frozen Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.4, 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CD161 (KLRB1) (Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1))
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别名
- CD161 / KLRB1
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背景
- Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 (CD161) protein contains an extracellular domain with several motifs characteristic of C type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus. In mouse the NKRP1 family has three members, NKRP1A, B and C, whilst in human only one member has been identified. The human protein has received the designation CD161, and the mouse proteins have been referred to as CD161a, b and c. Engagement of CD161c has been reported to have activating function in NK cells, whilst engagement of CD161b is inhibitory. CD161 is expressed by almost all NK cells and with a small subset of CD3+ve T cells. CD161 is a homodimeric cell surface protein, comprising two chains of 40-44kD.Synonyms: C-type lectin domain family 5 member B, CLEC5B, HNKR-P1a, Killer cell lectin-like receptor subfamily B member 1, NKRP1A, Natural killer cell surface protein P1A
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基因ID
- 3820
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NCBI登录号
- NP_002249
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UniProt
- Q12918
抗原
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