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CD86 抗体

CD86 适用: 人 FACS, IP, IHC (fro) 宿主: 小鼠 Monoclonal BU63 unconjugated
产品编号 ABIN319825
发货至: 中国
  • 抗原 See all CD86 抗体
    CD86
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    小鼠
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    单克隆
    标记
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    This CD86 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This antibody recognises CD86. Domain depletion epitope mapping studies indicate that the binding site of Mouse anti Human CD86, Clone Bu63 is located within the Ig-v-like domain of Human CD86 (Jeanin et al. 1997).
    纯化方法
    Affinity Chromatography on Protein A
    免疫原
    Human peripheral blood lymphocytes. Spleen cells from immunised mice were fused with cells of the P3 X63 Ag8.653 myeloma cell line.
    克隆位点
    BU63
    亚型
    IgG1
    Top Product
    Discover our top product CD86 Primary Antibody
  • 应用备注
    Immunoprecipitation. Flow Cytometry: 1/20-1/100, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunohistochemistry on Frozen Sections: 1/20-1/100. Recommended Positive Control: Tonsil.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    0.1 M Tris buffered saline, pH 8.2, 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CD86
    别名
    CD86 (CD86 产品)
    别名
    B7-2 antibody, B7.2 antibody, B70 antibody, CD28LG2 antibody, LAB72 antibody, B7 antibody, CLS1 antibody, Cd28l2 antibody, ETC-1 antibody, Ly-58 antibody, Ly58 antibody, MB7 antibody, MB7-2 antibody, TS/A-2 antibody, CD86 molecule antibody, CD86 antigen antibody, integrin subunit alpha 2b antibody, CD86 antibody, Cd86 antibody, Itga2b antibody
    背景
    CD86 is a 70kD cell surface protein expressed by activated B cells and monocytes. CD86 is also known as B7-2 and is the second ligand for CD28 and CTLA-4. It may have an important role in costimulation of T cells in the primary immune response.Synonyms: Activation B7-2 antigen, B7.2, B70, BU63, CD28LG2, CTLA-4 counter-receptor B7.2, FUN-1, T-lymphocyte activation antigen CD86
    基因ID
    942
    NCBI登录号
    NP_008820
    UniProt
    P42081
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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