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CD11b 抗体 (FITC)

Cited in 1 publication. This FITC-conjugated 小鼠 单克隆 anti-CD11b antibody (Clone ICRF44) specifically detects CD11b in FACS. The antibody is reactive with 人 和 猴 samples.
产品编号 ABIN319675
发货至: 中国
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Quick Overview for CD11b 抗体 (FITC) (ABIN319675)

抗原

See all CD11b (ITGAM) 抗体
CD11b (ITGAM) (Integrin alpha M (ITGAM))

适用

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人, 猴

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD11b antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)

克隆位点

ICRF44
  • 纯化方法

    Affinity Chromatography on Protein G.

    免疫原

    Rheumatoid synovial cells and human monocytes. Spleen cells from immunised BALB/c mice were fused with cells of the mouse Sp2/0 myeloma cell line.

    亚型

    IgG1
  • 应用备注

    Flow cytometry: neat - 1/10, use 10 μL of the suggested working dilution to label to label 10^6 cells in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Dilute only prior to immediate use. Avoid cycles of freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Sotiriou, Orlova, Al-Fakhri, Ihanus, Economopoulou, Isermann, Bdeir, Nawroth, Preissner, Gahmberg, Koschinsky, Chavakis: "Lipoprotein(a) in atherosclerotic plaques recruits inflammatory cells through interaction with Mac-1 integrin." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 20, Issue 3, pp. 559-61, (2006) (PubMed).

  • 抗原

    CD11b (ITGAM) (Integrin alpha M (ITGAM))

    别名

    CD11b

    背景

    CD11b is a 165kD molecule also known as the alpha M integrin, MAC-1 and CR3. This molecule is expressed as a heterodimer in association with the beta 2 integrin, and is found upon monocytes, granulocytes, NK cells and some peripheral blood lymphocytes.Synonyms: CD11 antigen-like family member B, CR-3 alpha chain, CR3A, Cell surface glycoprotein MAC-1 subunit alpha, ITGAM, Integrin alpha-M, Leukocyte adhesion receptor MO1, MAC1, Neutrophil adherence receptor

    基因ID

    3684

    NCBI登录号

    NP_000623

    UniProt

    P11215

    途径

    Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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