Aurora A 抗体 (pThr288)
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北京 101111
Quick Overview for Aurora A 抗体 (pThr288) (ABIN319281)
抗原
See all Aurora A (AURKA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr288
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特异性
- Aurora A (phospho-Thr288) Antibody AP08036PU detects endogenous levels of Aurora A only when phosphorylated at Threonine 288.
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纯化方法
- Immunoaffinity Chromatography: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
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免疫原
- The antiserum was produced against synthesized phosphopeptide derived from human Aurora A around the phosphorylation site of Threonine 288 (R-T-TP-L-M).
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应用备注
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Immunohistochemistry (1/50-1/100).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at-20 °C.
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- Aurora A (AURKA) (Aurora Kinase A (AURKA))
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别名
- Aurora Kinase A
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背景
- Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.Synonyms: AIK1, ARK1, AURA, AURKA, AURORA2, Aurora/IPL1-related kinase 1, BTAK, Breast tumor-amplified kinase, STK15, STK6, Serine/threonine kinase 15, Serine/threonine-protein kinase 6
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基因ID
- 6790
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NCBI登录号
- NP_003591
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UniProt
- O14965
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途径
- Cell Division Cycle, Asymmetric Protein Localization
抗原
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