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Aurora A 抗体 (pThr288)

The 兔 多克隆 anti-Aurora A antibody (ABIN319281) specifically detects Aurora A in IHC (p). The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN319281
发货至: 中国
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Quick Overview for Aurora A 抗体 (pThr288) (ABIN319281)

抗原

See all Aurora A (AURKA) 抗体
Aurora A (AURKA) (Aurora Kinase A (AURKA))

适用

  • 127
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  • 2
人, 小鼠

宿主

  • 122
  • 18
  • 1
  • 1

克隆类型

  • 104
  • 37
多克隆

标记

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  • 1
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This Aurora A antibody is un-conjugated

应用范围

  • 106
  • 50
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  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 23
    • 11
    • 9
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    • 6
    • 3
    • 3
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    • 2
    • 2
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    • 1
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    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    pThr288

    特异性

    Aurora A (phospho-Thr288) Antibody AP08036PU detects endogenous levels of Aurora A only when phosphorylated at Threonine 288.

    纯化方法

    Immunoaffinity Chromatography: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

    免疫原

    The antiserum was produced against synthesized phosphopeptide derived from human Aurora A around the phosphorylation site of Threonine 288 (R-T-TP-L-M).
  • 应用备注

    Immunohistochemistry (1/50-1/100).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody (in aliquots) at-20 °C.
  • 抗原

    Aurora A (AURKA) (Aurora Kinase A (AURKA))

    别名

    Aurora Kinase A

    背景

    Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.Synonyms: AIK1, ARK1, AURA, AURKA, AURORA2, Aurora/IPL1-related kinase 1, BTAK, Breast tumor-amplified kinase, STK15, STK6, Serine/threonine kinase 15, Serine/threonine-protein kinase 6

    基因ID

    6790

    NCBI登录号

    NP_003591

    UniProt

    O14965

    途径

    Cell Division Cycle, Asymmetric Protein Localization
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