EIF2S1 抗体 (pSer49)
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北京 101111
Quick Overview for EIF2S1 抗体 (pSer49) (ABIN319275)
抗原
See all EIF2S1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer49
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特异性
- Antibody detects endogenous levels of eIF2a only when phosphorylated at Serine 49.
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纯化方法
- Affinity Chromatography
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免疫原
- Synthetic phosphopeptide derived from human eIF2a around the phosphorylation site of Serine 49 (L-L-SP-E-L).
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应用备注
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Immunofluorescence: 1/100-1/200. Immunohistochemistry on Paraffin-Embedded Sections: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at-20 °C.
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- EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))
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别名
- EIF2A / EIF2S1
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背景
- The translation initiation factor eIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, eIF2, and GTP. eIF2 is composed of 3 nonidentical subunits, alpha (36 kD), beta (38 kD), and gamma (52 kD). The rate of formation of the ternary complex is modulated by the phosphorylation state of eIF2-alpha.Synonyms: EIF2-A, Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit alpha, eIF-2-alpha, eIF-2A, eIF-2alpha, eIF2 alpha
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基因ID
- 1965
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NCBI登录号
- NP_004085
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UniProt
- P05198
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途径
- Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C
抗原
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