GRIA2 抗体
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北京 101111
Quick Overview for GRIA2 抗体 (ABIN319147)
抗原
See all GRIA2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody is specific for glutamate receptor subunit 2 (GluR2), a component of the AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid) group of ionotropic glutamate receptors, which play a key role at excitatory synapses, including synaptic transmission, stabilisation and plasticity.
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纯化方法
- Affinity chromatography
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免疫原
- Keyhole limpet haemocyanin conjugated synthetic peptide corresponding to an amino acid sequence within rat GluR2.
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亚型
- IgG
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应用备注
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Western Blot: 1: 1000, detects a band of approximately 100 kDa in rat brain hippocampuscell lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 10 mM Hepes, pH 7.5 containing 0.09 % Sodium Azide, 0.01 % Bovine Serum Albumin, 50 % Glycerol
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))
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别名
- Glutamate Receptor 2 / GLUR2
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背景
- GluR2 is possibly the most important of the AMPA receptor subunits, responsible for AMPA receptor rectifying properties, control of ion flow and in particular the influx of calcium. The majority of GluR2 in the CNS is expressed in the GluR2(R) form, containing a critical arginine residue (as opposed to a glutamine residue) in the Transmembrane region 2 (TM2) domain, thereby rendering native AMPA receptors impermeable to calcium.Synonyms: AMPA-selective glutamate receptor 2, AMPA2, GRIA2, GluR-B, GluR-K2, Glutamate receptor ionotropic
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基因ID
- 2891
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NCBI登录号
- NP_000817
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UniProt
- P42262
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途径
- PI3K-Akt Signaling
抗原
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