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Tyrosine Hydroxylase 抗体 (pSer40)

Name: Tyrosine Hydroxylase 抗体 (pSer40)
SKU: ABIN319111
Availability: OutOfStock

TH 适用: 人, 大鼠, 小鼠, Pig WB, IF, IHC (fro) 宿主: 兔 Polyclonal unconjugated

产品编号 ABIN319111

发货至: 中国

Datasheet as PDF

抗原 See all Tyrosine Hydroxylase (TH) 抗体

Tyrosine Hydroxylase (TH)
抗原表位
16

15

12

10

9

4

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer40
适用
109

97

90

11

10

8

7

5

4

3

3

3

3

2

1

1

1

1

1
人, 大鼠, 小鼠, Pig
宿主
103

21

7

3

1
兔
Compatible Secondaries
克隆类型
105

30
多克隆
标记
84

8

5

5

5

5

5

5

2

2

2

1

1

1

1

1

1

1
This Tyrosine Hydroxylase antibody is un-conjugated
应用范围
94

64

34

19

18

18

15

15

14

13

6

3

3

3

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

特异性

This antibody reacts to is specific for Tyrosine Hydroxylase, when phosphorylated at serine 40.

纯化方法

Affinity chromatography

免疫原

Synthetic phosphopeptide corresponding to an amino acid sequence within Tyrosine Hydroxylase which includes phosphorylated Ser 40.

亚型

IgG

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anti-Tyrosine Hydroxylase (TH) (AA 101-165) antibody
TH 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-Tyrosine Hydroxylase (TH) (AA 82-310) antibody
TH 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Tyrosine Hydroxylase (TH) (pSer40) antibody
TH 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated

anti-Tyrosine Hydroxylase (TH) (pSer31) antibody
TH 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated

anti-Tyrosine Hydroxylase (TH) antibody
TH 适用: 人 WB, IF, IHC (p), ICC, IHC (fro), IHC (wm) 宿主: 兔 Polyclonal unconjugated

anti-Tyrosine Hydroxylase (TH) (AA 486-514) antibody
TH 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Tyrosine Hydroxylase (TH) (AA 34-301) antibody
TH 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Tyrosine Hydroxylase (TH) (pSer19) antibody
TH 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated

anti-Tyrosine Hydroxylase (TH) (C-Term) antibody
Verified TH 适用: 人 IHC, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Tyrosine Hydroxylase (TH) antibody
TH 适用: 人, 大鼠, 小鼠, Cat, 雪貂 WB, IHC, IF, ELISA, IHC (p), IP, IHC (fro) 宿主: 兔 Polyclonal unconjugated

应用备注

Immunohistochemistry on frozen sections: 1: 1000. Western Blot: 1: 1000,detects a band of approximately 60 kDa in PC-12 cell lysates,following stimulation by Okadaic acid. Immunofluorescence: 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
状态

Liquid

缓冲液

10 mM HEPES, pH 7.5 containing 0.09 % Sodium Azide, 0.01 % Bovine Serum Albumin and 50 % Glycerol

储存液

Sodium azide

注意事项

This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
抗原

Tyrosine Hydroxylase (TH)

别名

Tyrosine 3-Monooxygenase (TH) (TH 产品)

别名

DYT14 antibody, DYT5b antibody, TYH antibody, The antibody, CG10118 antibody, DH65B antibody, DTH antibody, Dmel\\CG10118 antibody, Pale antibody, Ple antibody, TH antibody, Th antibody, VII antibody, dTH1 antibody, dTH65B antibody, pale/ple antibody, th antibody, dyt14 antibody, dyt5b antibody, tyh antibody, tyrosine hydroxylase antibody, pale antibody, tyrosine 3-monooxygenase antibody, tyrosine hydroxylase S homeolog antibody, TH antibody, Th antibody, ple antibody, th antibody, th.S antibody, LOC100008895 antibody

背景

Tyrosine hydroxylase (TH) catalyzes the rate-limiting step in the biosynthetic pathway of the catecholamines dopamine (DA), norepinephrine, and epinephrine. The enzyme exists as a tetramer, with each subunit composed of an N-terminal regulatory domain and a C-terminal catalytic domain. Phosphorylation of TH has been shown to occur at several serine residues. Phosphorylation at serine 40 results in an increase in hydroxylase activity, and phosphorylation at serine 19 is reported to promote phosphorylation of the serine 40 residue. Tyrosine hydroxylase is regularly used as a marker for dopaminergic neurons, which is particularly relevant for research into ParkinsonSynonyms: TYH, Tyrosine 3-hydroxylase

基因ID

7054

NCBI登录号

NP_000351

UniProt

P07101

途径

Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour