DISC1 抗体 (Middle Region)
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Quick Overview for DISC1 抗体 (Middle Region) (ABIN318901)
抗原
See all DISC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- This antibody recognises disrupted in schizophrenia 1 (DISC1), 93 kDa protein located in the nucleus, cytoplasm and mitochondria.
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纯化方法
- Antisera to human DISC1 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.
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免疫原
- An 18 amino acid peptide located near the centre of human DISC1.
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亚型
- IgG
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anti-Disrupted in Schizophrenia 1 (DISC1) (AA 102-261) antibody
DISC1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Disrupted in Schizophrenia 1 (DISC1) antibodyDISC1 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Disrupted in Schizophrenia 1 (DISC1) (AA 1-200) antibodyDISC1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Disrupted in Schizophrenia 1 (DISC1) (C-Term) antibodyDISC1 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Disrupted in Schizophrenia 1 (DISC1) (C-Term) antibodyDISC1 适用: 人, 小鼠 WB, IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Disrupted in Schizophrenia 1 (DISC1) (AA 99-325) antibodyDISC1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Disrupted in Schizophrenia 1 (DISC1) (AA 461-477), (Middle Region) antibodyDISC1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Disrupted in Schizophrenia 1 (DISC1) (AA 101-200) antibodyDISC1 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Disrupted in Schizophrenia 1 (DISC1) (AA 761-832) antibodyDISC1 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Disrupted in Schizophrenia 1 (DISC1) (AA 700-728), (C-Term) antibodyDISC1 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1 - 2g/mL, detects bands of approximately 95100 kDa in SKNSH cell lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline containing 0.02 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- DISC1 (Disrupted in Schizophrenia 1 (DISC1))
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别名
- DISC1
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背景
- The DISC1 protein is widely expressed in normal tissues. It is involved in neurite outgrowth and cortical development through its interaction with a variety of proteins including lissencephaly-1 (LIS1), NudeE-like (NUDEL) and phosphodiesterase 4B. In certain cases of schizophrenia the DISC1 gene has been found to be disrupted by a t(1,11) (q42.1,q14.3) translocation, and studies suggest that DISC1 could be a candidate susceptibility gene for this condition.Synonyms: DISC-1, Disrupted in schizophrenia 1 protein, KIAA0457
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基因ID
- 27185
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NCBI登录号
- NP_001012975
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UniProt
- Q9NRI5
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途径
- Regulation of Cell Size
抗原
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