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TNNI3 抗体

The 山羊 多克隆 anti-TNNI3 antibody is suitable to detect TNNI3 in samples from 人. It has been validated for EIA.
产品编号 ABIN318833
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TNNI3 抗体 (ABIN318833)

抗原

See all TNNI3 抗体
TNNI3 (Cardiac Troponin I (TNNI3))

适用

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宿主

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山羊

克隆类型

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多克隆

标记

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This TNNI3 antibody is un-conjugated

应用范围

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Enzyme Immunoassay (EIA)
  • 特异性

    This antibody recognises human cardiac-specific troponin I, (TnI) an integral inhibitory protein of cardiac muscle which exists as a complex with troponin C (TnC) and troponin T (TnT).

    纯化方法

    Purified IgG prepared by Immunoaffinity chromatography

    免疫原

    Native human cardiac troponin I, purity greater than 98%.

    亚型

    IgG
  • 应用备注

    ELISA.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0mg/mL

    缓冲液

    PBS buffer pH 7.4 containing 0.09 % Sodium Azide (NaN3)

    储存液

    Sodium azide

    注意事项

    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    TNNI3 (Cardiac Troponin I (TNNI3))

    别名

    Cardiac Troponin I

    背景

    The TnT subunit of troponin binds to tropomyosin to form a troponin-tropomyosin complex, anchored in place by the binding of TnI to actin, within muscle thin filaments. Structural change resulting from the binding of calcium to specific sites on the regulatory TnC subunit, releases the inhibitory region of TnI from actin, enabling the attachment of the molecular motor protein myosin, allowing for muscle contraction and hence movement. The measurement of blood TnI and TnT levels is an important diagnostic indicator of heart muscle damage, and can be used to differentiate between angina and myocardic infarction in patients with chest pain. Troponin I has also been shown to inhibit angiogenesis in vivo and in vitro.Synonyms: TNNC1, TNNI3

    基因ID

    7137

    NCBI登录号

    NP_000354

    UniProt

    P19429
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