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STXBP1 抗体 (pSer515)

STXBP1 适用: 人, 小鼠, 大鼠, Cow, 猴, 犬, 非洲爪蟾, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN318802
发货至: 中国
  • 抗原 See all STXBP1 抗体
    STXBP1 (Syntaxin Binding Protein 1 (STXBP1))
    抗原表位
    • 15
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer515
    适用
    • 47
    • 40
    • 30
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 猴, 犬, 非洲爪蟾, 小鸡
    宿主
    • 57
    • 6
    • 2
    克隆类型
    • 59
    • 6
    多克隆
    标记
    • 38
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This STXBP1 antibody is un-conjugated
    应用范围
    • 49
    • 27
    • 13
    • 13
    • 13
    • 9
    • 8
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody recognises Munc-18 phosphorylated at serine 515.
    纯化方法
    Purified
    免疫原
    Phosphopeptide corresponding to amino acid sequence surrounding phosphorylated Ser515 of Munc-18.
    亚型
    IgG
    Top Product
    Discover our top product STXBP1 Primary Antibody
  • 应用备注
    Western Blot: 1: 1000, detects a band/s of approximately 65 kDa in rat cortex cell lysates.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    10 mM Hepes pH 7.5 containing 0.09 % Sodium Azide (NaN3), 50 % Glycerol and 0.01 % Bovine Serum Albumin
    储存液
    Sodium azide
    注意事项
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    STXBP1 (Syntaxin Binding Protein 1 (STXBP1))
    别名
    STXBP1 / UNC18A (STXBP1 产品)
    别名
    MUNC18-1 antibody, NSEC1 antibody, P67 antibody, RBSEC1 antibody, UNC18 antibody, AI317162 antibody, AI326233 antibody, MMS10-G antibody, Ms10g antibody, Munc-18a antibody, Munc18-1 antibody, N-sec1 antibody, Rb-sec1 antibody, Sxtbp1 antibody, Unc18-1 antibody, Unc18h antibody, nsec1 antibody, fj43h10 antibody, stxbp1 antibody, wu:fj36d12 antibody, wu:fj43h10 antibody, zgc:114171 antibody, rop antibody, unc18 antibody, hunc18 antibody, rbsec1 antibody, munc18-1 antibody, MGC146482 antibody, ANC18HA antibody, NSEC1A antibody, Sec1 antibody, n-sec1 antibody, nSec1 antibody, rbSec1 antibody, rbSec1A antibody, rbSec1B antibody, UNC18A antibody, si:rp71-10d23.3 antibody, syntaxin binding protein 1 antibody, syntaxin binding protein 1a antibody, syntaxin binding protein 1 L homeolog antibody, syntaxin binding protein 1b antibody, STXBP1 antibody, Stxbp1 antibody, stxbp1a antibody, stxbp1 antibody, Tb09.160.0780 antibody, stxbp1.L antibody, stxbp1b antibody
    背景
    Munc-18 is a 67 kDa member of the STXBP/UNC-18/SEC1 family. It is neural specific, expressed in the brain, spinal cord and at very high levels in axons. Munc-18 is crucial to calcium-dependent neurotransmitter release, facilitating synaptic vesicle docking and fusion. It inhibits the formation of soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor (SNARE) complex by binding syntaxin 1 preventing the other components (synaptobrevin and synaptosomal associated protein of 25 kDa (SNAP-25)) from binding. The function of Munc-18 is regulated by the phosphorylation of serine 515 by protein kinase C. Munc-18 is also involved in the onset of female puberty through its regulation of glutamate release.Synonyms: N-Sec1, Syntaxin-binding protein 1, Unc-18 homolog, Unc-18-1, Unc-18A
    基因ID
    25558
    NCBI登录号
    NP_037170
    UniProt
    P61765
    途径
    Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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