电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

STXBP1 抗体 (pSer515)

This 兔 多克隆 antibody specifically detects STXBP1 in WB. It exhibits reactivity toward 人, 小鼠, 大鼠, 猴, Cow, 犬, 小鸡 和 非洲爪蟾.
产品编号 ABIN318802
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for STXBP1 抗体 (pSer515) (ABIN318802)

抗原

See all STXBP1 抗体
STXBP1 (Syntaxin Binding Protein 1 (STXBP1))

适用

  • 64
  • 52
  • 41
  • 6
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
人, 小鼠, 大鼠, 猴, Cow, 犬, 小鸡, 非洲爪蟾

宿主

  • 70
  • 9
  • 2

克隆类型

  • 60
  • 21
多克隆

标记

  • 42
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This STXBP1 antibody is un-conjugated

应用范围

  • 64
  • 29
  • 25
  • 23
  • 17
  • 13
  • 13
  • 8
  • 5
  • 5
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer515

    特异性

    This antibody recognises Munc-18 phosphorylated at serine 515.

    纯化方法

    Purified

    免疫原

    Phosphopeptide corresponding to amino acid sequence surrounding phosphorylated Ser515 of Munc-18.

    亚型

    IgG
  • 应用备注

    Western Blot: 1: 1000, detects a band/s of approximately 65 kDa in rat cortex cell lysates.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    10 mM Hepes pH 7.5 containing 0.09 % Sodium Azide (NaN3), 50 % Glycerol and 0.01 % Bovine Serum Albumin

    储存液

    Sodium azide

    注意事项

    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    STXBP1 (Syntaxin Binding Protein 1 (STXBP1))

    别名

    STXBP1 / UNC18A

    背景

    Munc-18 is a 67 kDa member of the STXBP/UNC-18/SEC1 family. It is neural specific, expressed in the brain, spinal cord and at very high levels in axons. Munc-18 is crucial to calcium-dependent neurotransmitter release, facilitating synaptic vesicle docking and fusion. It inhibits the formation of soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor (SNARE) complex by binding syntaxin 1 preventing the other components (synaptobrevin and synaptosomal associated protein of 25 kDa (SNAP-25)) from binding. The function of Munc-18 is regulated by the phosphorylation of serine 515 by protein kinase C. Munc-18 is also involved in the onset of female puberty through its regulation of glutamate release.Synonyms: N-Sec1, Syntaxin-binding protein 1, Unc-18 homolog, Unc-18-1, Unc-18A

    基因ID

    25558

    NCBI登录号

    NP_037170

    UniProt

    P61765

    途径

    Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
You are here: