STXBP1 抗体 (pSer515)
Quick Overview for STXBP1 抗体 (pSer515) (ABIN318802)
抗原
See all STXBP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer515
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特异性
- This antibody recognises Munc-18 phosphorylated at serine 515.
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纯化方法
- Purified
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免疫原
- Phosphopeptide corresponding to amino acid sequence surrounding phosphorylated Ser515 of Munc-18.
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亚型
- IgG
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anti-Syntaxin Binding Protein 1 (STXBP1) (AA 74-168) antibody
STXBP1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 6D1 unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) (C-Term) antibodyVerified STXBP1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) (AA 295-594) antibodySTXBP1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) (AA 245-594) antibodySTXBP1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) (AA 74-169) antibodySTXBP1 适用: 人, 小鼠 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 6D1 unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) antibodySTXBP1 适用: 人, 小鼠, 猴 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) (C-Term) antibodySTXBP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) (AA 184-216), (N-Term) antibodySTXBP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) antibodySTXBP1 适用: 人, 小鼠, 大鼠, Cow WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) (AA 1-603) antibodySTXBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1: 1000, detects a band/s of approximately 65 kDa in rat cortex cell lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 10 mM Hepes pH 7.5 containing 0.09 % Sodium Azide (NaN3), 50 % Glycerol and 0.01 % Bovine Serum Albumin
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储存液
- Sodium azide
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注意事项
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- STXBP1 (Syntaxin Binding Protein 1 (STXBP1))
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别名
- STXBP1 / UNC18A
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背景
- Munc-18 is a 67 kDa member of the STXBP/UNC-18/SEC1 family. It is neural specific, expressed in the brain, spinal cord and at very high levels in axons. Munc-18 is crucial to calcium-dependent neurotransmitter release, facilitating synaptic vesicle docking and fusion. It inhibits the formation of soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor (SNARE) complex by binding syntaxin 1 preventing the other components (synaptobrevin and synaptosomal associated protein of 25 kDa (SNAP-25)) from binding. The function of Munc-18 is regulated by the phosphorylation of serine 515 by protein kinase C. Munc-18 is also involved in the onset of female puberty through its regulation of glutamate release.Synonyms: N-Sec1, Syntaxin-binding protein 1, Unc-18 homolog, Unc-18-1, Unc-18A
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基因ID
- 25558
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NCBI登录号
- NP_037170
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UniProt
- P61765
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途径
- Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
抗原
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