Ectodysplasin A2 Receptor 抗体
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Quick Overview for Ectodysplasin A2 Receptor 抗体 (ABIN318757)
抗原
See all Ectodysplasin A2 Receptor (EDA2R) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects human X-linked ectodermal dysplasia receptor (XEDAR).
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纯化方法
- Purified
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免疫原
- Recombinant human XEDAR.
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亚型
- IgG
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应用备注
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Western Blot: 0.5 - 2.0g/mL, detects a band of approximately 33 kDa in 293 cell lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline containing 0.02 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Ectodysplasin A2 Receptor (EDA2R)
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别名
- EDA2R / TNFRSF27
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背景
- XEDAR is a 33kD type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily. XEDAR is a homologue of the ectodermal dysplasia receptor (EDAR), and binds to an isoform of ectodysplasin termed EDA-A2. Binding of ectodysplasin to XEDAR results in the induction of apoptosis, and is thought to be involved ectodermal organ development. New evidence suggests XEDAR may also be involved in skeletal muscle development. Two predominant isoforms of XEDAR exist, XEDAR-s and XEDAR-L, produced by alternative splicing.Synonyms: EDA-A2 receptor, Tumor necrosis factor receptor superfamily member 27, UNQ2448/PRO5727/PRO34080, X-linked ectodysplasin-A2 receptor, XEDAR
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基因ID
- 60401
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NCBI登录号
- NP_001186616
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UniProt
- Q9HAV5
抗原
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