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BIK 抗体 (N-Term)

BIK 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN318742
发货至: 中国
  • 抗原 See all BIK 抗体
    BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))
    抗原表位
    • 18
    • 16
    • 8
    • 8
    • 8
    • 7
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 76
    • 17
    • 3
    • 1
    人, 小鼠
    宿主
    • 74
    • 2
    克隆类型
    • 74
    • 2
    多克隆
    标记
    • 33
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    This BIK antibody is un-conjugated
    应用范围
    • 58
    • 32
    • 32
    • 18
    • 14
    • 14
    • 10
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    特异性
    This antibody detects an epitope within the N-terminal (NT) region of Bcl-2-interacting killer (Bik) also known as natural born killer (Nbk).
    纯化方法
    Purified
    免疫原
    15 amino acid peptide from near the amino terminus of human Bik.
    亚型
    IgG
    Top Product
    Discover our top product BIK Primary Antibody
  • 应用备注
    Western Blot: 1 - 2g/mL, detects a band of approximately 18 kDa in Jurkat cell lysates.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, 0.02 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))
    别名
    BIK (BIK 产品)
    别名
    BIK antibody, Biklk antibody, Blk antibody, Nbk antibody, BIP1 antibody, BP4 antibody, NBK antibody, si:dkey-31f5.6 antibody, BCL2 interacting killer antibody, BCL2-interacting killer antibody, BCL2-interacting killer (apoptosis-inducing) antibody, BIK antibody, Bik antibody, bik antibody
    背景
    Bik is a Bcl-2 homology domain 3 (BH3)-only protein of 18kD which requires the BAX gene for activation. Bik forms heterodimers with various antiapoptotic proteins such as Bcl-2 and Bcl-XL, inhibiting their antiapoptotic function. This can result in the release of Ca2+ and cytochrome C into the cytosol, leading to apoptosis. Loss of Bik is a common feature of clear-cell renal cell carcinoma (RCC), and is thought to act as a renal tissue-specific tumour suppressor gene.Synonyms: Apoptosis inducer NBK, BIP1, BP4, Bcl-2-interacting killer, NBK
    基因ID
    638
    NCBI登录号
    NP_001188
    UniProt
    Q13323
    途径
    Positive Regulation of Endopeptidase Activity
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