BIK 抗体 (N-Term)
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Quick Overview for BIK 抗体 (N-Term) (ABIN318742)
抗原
See all BIK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects an epitope within the N-terminal (NT) region of Bcl-2-interacting killer (Bik) also known as natural born killer (Nbk).
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纯化方法
- Purified
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免疫原
- 15 amino acid peptide from near the amino terminus of human Bik.
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亚型
- IgG
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anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) antibody
BIK 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (AA 1-123) antibodyBIK 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (AA 39-74) antibodyBIK 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB3381 unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (AA 37-136) antibodyBIK 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4G12 unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (pThr33) antibodyBIK 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (N-Term) antibodyBIK 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (N-Term) antibodyBIK 适用: 人, 小鼠 WB, IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (AA 37-136) antibodyBIK 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4G12 unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (pThr33) antibodyBIK 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (pThr33) antibodyBIK 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB7170 unconjugated
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应用备注
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Western Blot: 1 - 2g/mL, detects a band of approximately 18 kDa in Jurkat cell lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, 0.02 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))
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别名
- BIK
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背景
- Bik is a Bcl-2 homology domain 3 (BH3)-only protein of 18kD which requires the BAX gene for activation. Bik forms heterodimers with various antiapoptotic proteins such as Bcl-2 and Bcl-XL, inhibiting their antiapoptotic function. This can result in the release of Ca2+ and cytochrome C into the cytosol, leading to apoptosis. Loss of Bik is a common feature of clear-cell renal cell carcinoma (RCC), and is thought to act as a renal tissue-specific tumour suppressor gene.Synonyms: Apoptosis inducer NBK, BIP1, BP4, Bcl-2-interacting killer, NBK
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基因ID
- 638
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NCBI登录号
- NP_001188
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UniProt
- Q13323
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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