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BAG1 抗体 (C-Term)

BAG1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN318738
发货至: 中国
  • 抗原 See all BAG1 抗体
    BAG1 (BCL2-Associated Athanogene (BAG1))
    抗原表位
    • 4
    • 3
    • 3
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 34
    • 19
    • 17
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 31
    • 8
    克隆类型
    • 30
    • 9
    多克隆
    标记
    • 32
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BAG1 antibody is un-conjugated
    应用范围
    • 31
    • 14
    • 12
    • 11
    • 10
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
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    Western Blotting (WB)
    特异性
    This antibody detects an epitope within the C-terminal (CT) region of Bcl-2 associated athanogene-1 (BAG1).
    纯化方法
    Purified
    免疫原
    14 amino acid peptide from near the carboxy terminus of human BAG1.
    亚型
    IgG
    Top Product
    Discover our top product BAG1 Primary Antibody
  • 应用备注
    Western Blot: 1 - 2g/mL, detects a band of approximately 39 kDa in PC3 cell lysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0mg/mL
    缓冲液
    Phosphate buffered saline containing 0.02 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    BAG1 (BCL2-Associated Athanogene (BAG1))
    别名
    BAG1 (BAG1 产品)
    别名
    BAG-1 antibody, HAP antibody, RAP46 antibody, Rap46 antibody, Bag-1 antibody, ATBAG1 antibody, BCL-2-associated athanogene 1 antibody, MSG15.15 antibody, MSG15_15 antibody, im:7148830 antibody, si:dkey-216e9.4 antibody, BCL2 associated athanogene 1 antibody, putative bcl2-associated athanogene antibody, BCL2-associated athanogene 1 antibody, Bcl2 associated athanogene 1 antibody, BAG family molecular chaperone regulator 1 antibody, BCL-2-associated athanogene 1 antibody, BAG1 antibody, Smp_005900 antibody, Bag1 antibody, bag-1 antibody, LOC781741 antibody, bag1 antibody
    背景
    BAG1 is a co-chaperone protein which binds to and regulates the 70kD heat shock proteins (Hsp70/Hsc70). BAG1 has also been shown to interact with the kinase Raf1, a number of steroid and tyrosine kinase receptors, and the Bcl-2 family of proteins. It is thought to function as a molecular switch between cell growth and differentiation, and cell survival. The BAG1 gene encodes three different isoforms, a predominantly cytosolic form of 36kD (BAG1S), a 46kD cytosolic and nuclear form (BAG1M), and a predominantly nuclear form 50kD (BAG1L). BAG1 displays potent neuroprotective activity in vivo against stroke, and could be used for reducing brain injury during cerebral ischemia and neurodegenerative diseases. BAG1 may also promote chemoresistance, growth factor independence, and anchorage independent cell growth in tumour cells.Synonyms: BAG family molecular chaperone regulator 1, BAG-1, Bcl-2-associated athanogene 1, Glucocorticoid receptor-associated protein RAP46, HAP, RAP46
    基因ID
    573
    NCBI登录号
    NP_001165886
    UniProt
    Q99933
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