Tetanus Toxin 抗体
This anti-Tetanus Toxin antibody is a 山羊 多克隆 antibody detecting Tetanus Toxin in WB 和 EIA. Suitable for Clostridium tetani.
Quick Overview for Tetanus Toxin 抗体 (ABIN318666)
抗原
See all Tetanus Toxin (TetX) 抗体
Tetanus Toxin (TetX)
适用
Clostridium tetani
宿主
山羊
克隆类型
多克隆
标记
This Tetanus Toxin antibody is un-conjugated
应用范围
Western Blotting (WB), Enzyme Immunoassay (EIA)
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特异性
- This antibody detects the tetanus toxin which is produced by the soil micro-organism Clostridium tetani. C. tetani infection results in its systemic growth and secretion of tetanus, which causes muscle spasms by inhibiting neurotransmitter release. The antibody also reacts with the C-fragment of tetanus toxin.
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纯化方法
- Affinity Chromatography.
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免疫原
- Tetanus Exotoxin
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亚型
- IgG
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应用备注
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ELISA: 1g/mL. Western Blot: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 5.0 mg/mL
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缓冲液
- PBS pH 7.2 containing 0.09 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Tetanus Toxin (TetX)
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别名
- Tetanus Toxin
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物质类
- Bacteria
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背景
- Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the 76-Gln-|-Phe-77 bond of synaptobrevin-2. The precursor polypeptide is subsequently cleaved to yield subchains L and H. These remain linked by a disulfide bridge and are non-toxic after separation.Synonyms: Clostridium tetani toxin, tetX
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基因ID
- 1061100
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NCBI登录号
- NP_783831
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UniProt
- P04958
抗原
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