Methamphetamine 抗体
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北京 101111
Quick Overview for Methamphetamine 抗体 (ABIN318601)
抗原
宿主
克隆类型
标记
应用范围
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纯化方法
- Purified IgG prepared by affinity chromatography on Protein G
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免疫原
- Para-amino-metamphetamine conjugated to keyhole limpet hemocyanin
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亚型
- IgG
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应用备注
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ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 5.0 mg/mL
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缓冲液
- Phosphate buffered saline containing 0.09 % Sodium Azide (NaN3)
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储存液
- Sodium azide
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注意事项
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Methamphetamine (M-Amp)
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别名
- Methamphetamine
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物质类
- Chemical
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背景
- Methamphetamine (METH) is closely related chemically to amphetamine (AMPH). METH is a potent central nervous system stimulant with additional peripheral sympathomimetic effects. METH and AMPH have been used clinically in the treatment of obesity, minimal brain dysfunction, narcolepsy, depression and to counter fatigue. They are also subjected to widespread abuse. METH is an indirect agonists. It causes the release of newly synthesized norepinephrine and dopamine and it blocks the re uptake of these transmitters from the synapse. This can lead to an increase in the concentration of catecholamines in the synapse as well as an overall increase in catecholaminergic activity in the brain. The mechanism of METH induced neurotoxicity for all monoaminergic cell types may lie primarily with the dopaminergic system in the striatum. It may also lie with the interaction between METH induced release of dopamine and its ability to inhibit monoamine oxidase.
抗原
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